Evidence map›Paper›PMID 34367659›Full record

ArticleEvolution letters2021

Selection in males purges the mutation load on female fitness.

Karl Grieshop, Paul L Maurizio, Göran Arnqvist, David Berger

Abstract read
In one paragraph

Article in Evolution letters, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Sexual selection purges mutation load, but not overall genetic diversity, decreasing vulnerability to extinction.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  3. Article
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  6. Sex-specific viability effects of mutations in Drosophila melanogaster.Evolution; international journal of organic evolution · 2024
    Article
  7. Article
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  13. Review
  14. Article
  15. The genetic architecture of sexual dimorphism in the mossProceedings. Biological sciences · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Karl GrieshopAnimal Ecology, Department of Ecology and Genetics Uppsala University Uppsala SE-75236 Sweden.ORCID https://orcid.org/0000-0001-8925-5066
Paul L MaurizioSection of Genetic Medicine, Department of Medicine University of Chicago Chicago Illinois 60637.ORCID https://orcid.org/0000-0002-5859-6260
Göran ArnqvistAnimal Ecology, Department of Ecology and Genetics Uppsala University Uppsala SE-75236 Sweden.ORCID https://orcid.org/0000-0002-3501-3376
David BergerAnimal Ecology, Department of Ecology and Genetics Uppsala University Uppsala SE-75236 Sweden.ORCID https://orcid.org/0000-0003-0196-6109

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Theory predicts that the ability of selection and recombination to purge mutation load is enhanced if selection against deleterious genetic variants operates more strongly in males than females. However, direct empirical support for this tenet is limited, in part because traditional quantitative genetic approaches allow dominance and intermediate-frequency polymorphisms to obscure the effects of the many rare and partially recessive deleterious alleles that make up the main part of a population's mutation load. Here, we exposed the partially recessive genetic load of a population of

Indexed as

Diallel crossfitnessgood genesheterosismutation loadsexual selection

Identifiers

PMID34367659
PMCPMC8327962

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.