Evidence map›Paper›PMID 34367556›Full record

ArticleEcology and evolution2021

Balancing selection, genetic drift, and human-mediated introgression interplay to shape MHC (functional) diversity in Mediterranean brown trout.

Lorenzo Talarico, Silvio Marta, Anna Rita Rossi, Simone Crescenzo, Gerardo Petrosino, Marco Martinoli, Lorenzo Tancioni

Open access · goldAbstract read
In one paragraph

Article in Ecology and evolution, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 18 citations in OpenAlex.

  1. AncestralAnimals : an open access journal from MDPI · 2026
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  6. Unveiling MHC-Biology · 2024
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  11. Review
  12. Evaluating the Potential Fitness Effects of Chinook Salmon (Animals : an open access journal from MDPI · 2023
    Article
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  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Lorenzo TalaricoLaboratory of Experimental Ecology and Aquaculture Department of Biology University of Rome "Tor Vergata" Rome Italy.ORCID https://orcid.org/0000-0002-5037-2676
Silvio MartaDepartment of Environmental Science and Policy University of Milan Milan Italy.ORCID https://orcid.org/0000-0001-8850-610X
Anna Rita RossiDepartment of Biology and Biotechnology C. Darwin University of Rome "La Sapienza" Rome Italy.ORCID https://orcid.org/0000-0003-4049-1249
Simone CrescenzoDepartment of Biology and Biotechnology C. Darwin University of Rome "La Sapienza" Rome Italy.
Gerardo PetrosinoDepartment of Biology and Biotechnology C. Darwin University of Rome "La Sapienza" Rome Italy.ORCID https://orcid.org/0000-0002-2747-8528
Marco MartinoliLaboratory of Experimental Ecology and Aquaculture Department of Biology University of Rome "Tor Vergata" Rome Italy.ORCID https://orcid.org/0000-0002-3670-9711
Lorenzo TancioniLaboratory of Experimental Ecology and Aquaculture Department of Biology University of Rome "Tor Vergata" Rome Italy.ORCID https://orcid.org/0000-0001-6823-4872
Sapienza University of Rome · ITUniversity of Rome Tor Vergata · ITUniversity of Milan · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The extraordinary polymorphism of major histocompatibility complex (MHC) genes is considered a paradigm of pathogen-mediated balancing selection, although empirical evidence is still scarce. Furthermore, the relative contribution of balancing selection to shape MHC population structure and diversity, compared to that of neutral forces, as well as its interaction with other evolutionary processes such as hybridization, remains largely unclear. To investigate these issues, we analyzed adaptive (MHC-DAB gene) and neutral (11 microsatellite loci) variation in 156 brown trout (

Indexed as

body conditionhybridizationmajor histocompatibility complexMHC supertypesrare allele advantageSalmo trutta complex

Identifiers

PMID34367556
PMCPMC8328470
OpenAlexW3178795995

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.