Evidence map›Paper›PMID 34367476›Full record

ReviewWorld journal of stem cells2021

Stem cell therapies in tendon-bone healing.

Yue Xu, Wan-Xia Zhang, Li-Na Wang, Yue-Qing Ming, Yu-Lin Li, Guo-Xin Ni

Open access · hybridAbstract readReview
In one paragraph

Review in World journal of stem cells, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed
5.9field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 55 citations in OpenAlex.

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  11. Total Flavonoids ofBiology · 2025
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  15. [Effect of autologous osteochondral tissue and periosteum transplantation on tendon-bone healing of rotator cuff in rabbits].Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Yue XuSchool of Sports Medicine and Rehabilitation, Beijing Sport University, Beijing 100084, China.
Wan-Xia ZhangSchool of Sports Medicine and Rehabilitation, Beijing Sport University, Beijing 100084, China.
Li-Na WangSchool of Sports Medicine and Rehabilitation, Beijing Sport University, Beijing 100084, China.
Yue-Qing MingSchool of Sports Medicine and Rehabilitation, Beijing Sport University, Beijing 100084, China.
Yu-Lin LiSchool of Sports Medicine and Rehabilitation, Beijing Sport University, Beijing 100084, China.
Guo-Xin NiSchool of Sports Medicine and Rehabilitation, Beijing Sport University, Beijing 100084, China. fjrehab@163.com.
Beijing Sport University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tendon-bone insertion injuries such as rotator cuff and anterior cruciate ligament injuries are currently highly common and severe. The key method of treating this kind of injury is the reconstruction operation. The success of this reconstructive process depends on the ability of the graft to incorporate into the bone. Recently, there has been substantial discussion about how to enhance the integration of tendon and bone through biological methods. Stem cells like bone marrow mesenchymal stem cells (MSCs), tendon stem/progenitor cells, synovium-derived MSCs, adipose-derived stem cells, or periosteum-derived periosteal stem cells can self-regenerate and potentially differentiate into different cell types, which have been widely used in tissue repair and regeneration. Thus, we concentrate in this review on the current circumstances of tendon-bone healing using stem cell therapy.

Indexed as

Anterior cruciate ligamentBoneRotator cuffStem cellTendon

Identifiers

PMID34367476
PMCPMC8316867
OpenAlexW3185792777

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.