Evidence map›Paper›PMID 34367300›Full record

ArticleEvidence-based complementary and alternative medicine : eCAM2021

Desmond Omane Acheampong, Isaac Kyei Baffour, Victor Yao Atsu Barku, Justice Kwaku Addo, Mainprice Akuoko Essuman, Alex Boye

Open access · hybridAbstract read
In one paragraph

Article in Evidence-based complementary and alternative medicine : eCAM, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Antitumor components and mechanisms ofFrontiers in pharmacology · 2025
    Review
  3. Journal of Taibah University Medical Sciences · 2024
    Article
  4. Review
  5. The Hepatocurative Effects ofIndian journal of clinical biochemistry : IJCB · 2024
    Article
  6. BioMed research international · 2024
    Article
  7. Article
  8. Wound Healing Properties and Antimicrobial Effects ofBioMed research international · 2022
    Article
  9. Article
  10. Antimicrobial Activity against Oral Pathogens Confirms the Use ofEvidence-based complementary and alternative medicine : eCAM · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Desmond Omane AcheampongDepartment of Biomedical Sciences, School of Allied Health Sciences, College of Health and Allied Sciences, University of Cape Coast, Cape Coast, Ghana.
Isaac Kyei BaffourDepartment of Biomedical Sciences, School of Allied Health Sciences, College of Health and Allied Sciences, University of Cape Coast, Cape Coast, Ghana.ORCID https://orcid.org/0000-0001-5813-8481
Victor Yao Atsu BarkuDepartment of Chemistry, School of Physical Sciences, College of Agriculture and Natural Sciences, University of Cape Coast, Cape Coast, Ghana.
Justice Kwaku AddoDepartment of Chemistry, School of Physical Sciences, College of Agriculture and Natural Sciences, University of Cape Coast, Cape Coast, Ghana.
Mainprice Akuoko EssumanDepartment of Medical Laboratory Science, School of Allied Health Sciences, College of Health and Allied Sciences, University of Cape Coast, Cape Coast, Ghana.ORCID https://orcid.org/0000-0002-4641-2647
Alex BoyeDepartment of Medical Laboratory Science, School of Allied Health Sciences, College of Health and Allied Sciences, University of Cape Coast, Cape Coast, Ghana.ORCID https://orcid.org/0000-0002-1133-0940
University of Cape Coast · GH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDespite the enrollment of new small molecules such as Sorafenib for the treatment of hepatocellular carcinoma (HCC), HCC still remains a significant contributor to cancer-related mortality and morbidity globally.

objectiveThis study assessed the effects of an alkaloidal extract of the leaves of MATERIALS AND

methods

resultsZZAE (100 and 200 mg/kg) and carvedilol decreased tumor incidence compared to that of control. Compared to control, ZZAE (100 and 200 mg/kg) significantly (

conclusionZZAE ameliorated CCl

Identifiers

PMID34367300
PMCPMC8337135
OpenAlexW3184956681

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.