Evidence map›Paper›PMID 34367237›Full record

ArticleFrontiers in genetics2021

Genetic Modulation of Initial Sensitivity to Δ9-Tetrahydrocannabinol (THC) Among the BXD Family of Mice.

Cory Parks, Chris M Rogers, Pjotr Prins, Robert W Williams, Hao Chen, Byron C Jones, Bob M Moore, Megan K Mulligan

Open access · goldAbstract read
In one paragraph

Article in Frontiers in genetics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.3field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Cory ParksDepartment of Genetics, Genomics and Informatics, The University of Tennessee Health Science Center, Memphis, TN, United States.
Chris M RogersDepartment of Genetics, Genomics and Informatics, The University of Tennessee Health Science Center, Memphis, TN, United States.
Pjotr PrinsDepartment of Genetics, Genomics and Informatics, The University of Tennessee Health Science Center, Memphis, TN, United States.
Robert W WilliamsDepartment of Genetics, Genomics and Informatics, The University of Tennessee Health Science Center, Memphis, TN, United States.
Hao ChenDepartment of Pharmacology, Addiction Science and Toxicology, The University of Tennessee Health Science Center, Memphis, TN, United States.
Byron C JonesDepartment of Genetics, Genomics and Informatics, The University of Tennessee Health Science Center, Memphis, TN, United States.
Bob M MooreDepartment of Pharmaceutical Sciences, The University of Tennessee Health Science Center, Memphis, TN, United States.
Megan K MulliganDepartment of Genetics, Genomics and Informatics, The University of Tennessee Health Science Center, Memphis, TN, United States.
University of Tennessee Health Science Center · US

Funding

TIM Project NIDA P30 CenterP30DA044223 · NIDA · UNIVERSITY OF TENNESSEE HEALTH SCI CTR · PI SABA, LAURA MAREN · 2017 to 2021
$3.9M
A Unified High Performance Web Service for Systems Genetics and Precision MedicineR01GM123489 · NIGMS · UNIVERSITY OF TENNESSEE HEALTH SCI CTR · PI PRINS, PJOTR, SEN, SAUNAK · 2017 to 2024
$3.7M
NIDA NIH HHS P30 DA044223NIGMS NIH HHS R01 GM123489
6 · The paper itself

Abstract

Cannabinoid receptor 1 activation by the major psychoactive component in cannabis, Δ9-tetrahydrocannabinol (THC), produces motor impairments, hypothermia, and analgesia upon acute exposure. In previous work, we demonstrated significant sex and strain differences in acute responses to THC following administration of a single dose (10 mg/kg,

Indexed as

addictionBXD familyC57BL/6cannabisDBA/2drug responseQTLTHC

Identifiers

PMID34367237
PMCPMC8343140
OpenAlexW3183142033

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.