Evidence map›Paper›PMID 34367171›Full record

ArticleFrontiers in immunology2021

Human Placental Trophoblasts Infected by

Lauren J Johnson, Siavash Azari, Amy Webb, Xiaoli Zhang, Mikhail A Gavrilin, Joanna M Marshall, Kara Rood, Stephanie Seveau

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
4.1field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 32 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Article
  6. Transcriptomic comparison of in vitro models of the human placenta.bioRxiv : the preprint server for biology · 2024
    Article
  7. Bacterial aggregation facilitates internalin-mediated invasion ofFrontiers in cellular and infection microbiology · 2024
    Article
  8. Review
  9. Review
  10. Placental Listeriosis: Case Report and Literature Review.The American journal of tropical medicine and hygiene · 2023
    Review
  11. Article
  12. Intrinsic signalling factors associated with cancer cell-cell fusion.Cell communication and signaling : CCS · 2023
    Review
  13. Human Listeriosis.Clinical microbiology reviews · 2023
    Review
  14. Article
  15. Article
  16. Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Lauren J JohnsonDepartment of Microbial Infection and Immunity, The Ohio State University, Columbus, OH, United States.
Siavash AzariDepartment of Microbial Infection and Immunity, The Ohio State University, Columbus, OH, United States.
Amy WebbDepartment of Biomedical Informatics, The Ohio State University, Columbus, OH, United States.
Xiaoli ZhangDepartment of Biomedical Informatics, Center for Biostatistics, The Ohio State University, Columbus, OH, United States.
Mikhail A GavrilinPulmonary, Critical Care and Sleep Medicine Division, Department of Internal Medicine, The Ohio State University, Columbus, OH, United States.
Joanna M MarshallDepartment of Microbial Infection and Immunity, The Ohio State University, Columbus, OH, United States.
Kara RoodDepartment of Obstetrics and Gynecology, Division of Maternal Fetal Medicine, The Ohio State University, Columbus, OH, United States.
Stephanie SeveauDepartment of Microbial Infection and Immunity, The Ohio State University, Columbus, OH, United States.
The Ohio State University · US

Funding

The Ohio State University Center for clinical and Translational ScienceUL1TR001070 · NCATS · OHIO STATE UNIVERSITY · PI JACKSON, REBECCA D · 2013 to 2017
$22.6M
Host Responses to the Pore-Forming Toxin Listeriolysin OR01AI157205 · NIAID · OHIO STATE UNIVERSITY · PI AMER, AMAL O, BOYAKA, PROSPER N · 2021 to 2025
$3.2M
Interdisciplinary Program in Microbe-Host BiologyT32AI112542 · NIAID · OHIO STATE UNIVERSITY · PI JUSTICE, SHERYL S, WOZNIAK, DANIEL J · 2014 to 2018
$644k
Mechanistic study of human placental infection by Listeria monocytogenesR21AI105588 · NIAID · OHIO STATE UNIVERSITY · PI SEVEAU, STEPHANIE M M · 2014 to 2015
$424k
Establishing the roles of lncRNAs in placental infection by Listeria monocytogenesR03AI149371 · NIAID · OHIO STATE UNIVERSITY · PI SEVEAU, STEPHANIE M M · 2020 to 2021
$156k
NCATS NIH HHS UL1 TR001070NIAID NIH HHS R03 AI149371NIAID NIH HHS R21 AI105588NIAID NIH HHS T32 AI112542
6 · The paper itself

Abstract

The placenta controls the growth of the fetus and ensures its immune protection. Key to these functions, the syncytiotrophoblast (SYN) is a syncytium formed by fusion of underlying mononuclear trophoblasts. The SYN covers the placental surface and is bathed in maternal blood to mediate nutritional and waste exchanges between the mother and fetus. The bacterial pathogen

Indexed as

Bacterial ProteinsCells, CulturedChemokinesCytokinesFemaleGiant CellsHumansInflammationListeria monocytogenesMembrane ProteinsPregnancyPregnancy OutcomeTranscriptomeTrophoblastsBacterial ProteinsChemokinesCytokinesinlB protein, Listeria monocytogenesinternalin protein, BacteriaMembrane ProteinsfusioninfectioninflammationListeria monocytogenesplacentapregnancy complicationsRNAseqtrophoblast

Identifiers

PMID34367171
PMCPMC8346206
OpenAlexW3186817848

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.