Evidence map›Paper›PMID 34367162›Full record

Trial reportFrontiers in immunology2021

Adapting Rapid Diagnostic Tests to Detect Historical Dengue Virus Infections.

Fernando Echegaray, Peter Laing, Samantha Hernandez, Sully Marquez, Amanda Harris, Ian Laing, Adam Chambers, Neil McLennan, Victor A Sugiharto, Hua-Wei Chen and 14 more

Open access · goldAbstract readClinical TrialMulticenter Study
In one paragraph

Trial report in Frontiers in immunology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 16 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

24 authors at 11 institutions in 3 countries.

Fernando EchegarayViral Epidemiology and Immunity Unit, Laboratory of Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, United States.
Peter LaingExcivion Ltd., Cambridge, United Kingdom.
Samantha HernandezDivision of Infectious Diseases and Vaccinology, School of Public Health, University of California, Berkeley, Berkeley, CA, United States.
Sully MarquezInstituto de Microbiología, Universidad San Francisco de Quito, Quito, Ecuador.
Amanda HarrisExcivion Ltd., Cambridge, United Kingdom.
Ian LaingExcivion Ltd., Cambridge, United Kingdom.
Adam ChambersOxford Expression Technologies Ltd., Oxford, United Kingdom.
Neil McLennanGlobalDX Ltd., Mensrie, United Kingdom.
Victor A SugihartoViral & Rickettsial Diseases Department, Naval Medical Research Center, Silver Spring, MD, United States.
Hua-Wei ChenViral & Rickettsial Diseases Department, Naval Medical Research Center, Silver Spring, MD, United States.
Sandra Vivero VillagranInstituto de Investigación en Biomedicina (Inbiomed), Universidad Central, Quito, Ecuador.
Abigail CollingwoodDepartment of Epidemiology, University of Michigan School of Public Health, Ann Arbor, MI, United States.
Magelda MontoyaDivision of Infectious Diseases and Vaccinology, School of Public Health, University of California, Berkeley, Berkeley, CA, United States.
Fausto Bustos CarrilloDivision of Infectious Diseases and Vaccinology, School of Public Health, University of California, Berkeley, Berkeley, CA, United States.
Mark P SimonsViral & Rickettsial Diseases Department, Naval Medical Research Center, Silver Spring, MD, United States.
Philip J CooperDepartment of Infection and Immunity, St George's University of London, London, United Kingdom.
Andrea LopezSchool of Medicine, Universidad International del Ecuador, Quito, Ecuador.
Gabriel TruebaInstituto de Microbiología, Universidad San Francisco de Quito, Quito, Ecuador.
Joseph EisenbergDepartment of Epidemiology, University of Michigan School of Public Health, Ann Arbor, MI, United States.
Shuenn-Jue WuViral & Rickettsial Diseases Department, Naval Medical Research Center, Silver Spring, MD, United States.
William MesserDepartment of Molecular Microbiology and Immunology, Oregon Health and Sciences University, Portland, OR, United States.
Eva HarrisDivision of Infectious Diseases and Vaccinology, School of Public Health, University of California, Berkeley, Berkeley, CA, United States.
Josefina ColomaDivision of Infectious Diseases and Vaccinology, School of Public Health, University of California, Berkeley, Berkeley, CA, United States.
Leah C KatzelnickViral Epidemiology and Immunity Unit, Laboratory of Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, United States.
University of California, Berkeley · USNaval Medical Research Command · USExcivion (United Kingdom) · GBNational Institutes of Health · USUniversidad San Francisco de Quito · ECUniversity of Michigan–Ann Arbor · USCentral University of Ecuador · ECOregon Health & Science University · USOxford Technologies (United Kingdom) · GBSt George's, University of London · GBUniversidad Internacional del Ecuador · EC

Funding

T Cell Responses Following DENV Natural Infections and Live-Attenuated Dengue Virus VaccinationP01AI106695 · NIAID · UNIVERSITY OF CALIFORNIA BERKELEY · PI Aravinda M. DeSilva · 2015 to 2026
$34.1M
Oregon Clinical and Translational Research InstituteUL1TR000128 · NCATS · OREGON HEALTH & SCIENCE UNIVERSITY · PI ELLISON, DAVID H · 2012 to 2015
$28.7M
Research Mentoring and Building Capacity of underrepresented Minority Research Scientists in India.D43TW010540 · FIC · YALE UNIVERSITY · PI MICHELE BARRY, Eva Harris · 2017 to 2026
$15.5M
American Asian Centers for Arbovirus Research and Enhanced Surveillance (A2CARES)U01AI151788 · NIAID · UNIVERSITY OF CALIFORNIA BERKELEY · PI Josefina Coloma, Eva Harris · 2020 to 2026
$9.6M
Immunology, virology, and epidemiology of flaviviruses and other emerging virusesZIAAI001346 · NIAID · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · PI KATZELNICK, LEAH · 2021 to 2025
$7.1M
Living in the post-Zika world: Impact of interactions between dengue and Zika viruses on diagnostics, antibody dynamics, and correlates of disease riskU01AI153416 · NIAID · UNIVERSITY OF CALIFORNIA BERKELEY · PI HARRIS, EVA · 2021 to 2025
$4.9M
Zika and Dengue Co-circulation Under Environmental Change and UrbanizationR01AI132372 · NIAID · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI COLOMA, JOSEFINA, EISENBERG, JOSEPH N. S. · 2017 to 2020
$2.9M
Epidemiological, Clinical & Immunological Studies of Zika, dengue and chikungunyaR01AI099631 · NIAID · SUSTAINABLE SCIENCES INSTITUTE · PI BALMASEDA, ANGEL LAZARO · 2012 to 2021
$1.8M
Dengue virus immunity in endemic and non-endemic human cohortsR21AI135537 · NIAID · OREGON HEALTH & SCIENCE UNIVERSITY · PI MESSER, WILLIAM · 2018 to 2019
$439k
FIC NIH HHS D43 TW010540NCATS NIH HHS UL1 TR000128NIAID NIH HHS P01 AI106695NIAID NIH HHS R01 AI099631NIAID NIH HHS R01 AI132372NIAID NIH HHS R21 AI135537NIAID NIH HHS U01 AI151788NIAID NIH HHS U01 AI153416
6 · The paper itself

Abstract

The only licensed dengue vaccine, Dengvaxia

Indexed as

DengueDiagnostic Tests, RoutineAdolescentAdultAgedAged, 80 and overAntibodies, ViralChildChild, PreschoolDengue VaccinesDengue VirusFemaleHumansImmunoglobulin GImmunoglobulin MInfantAntibodies, ViralDengue VaccinesImmunoglobulin GImmunoglobulin Mdenguedengue vaccinepre-vaccination screeningrapid diagnostic testZika

Identifiers

PMID34367162
PMCPMC8344047
OpenAlexW3184224233

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.