Evidence map›Paper›PMID 34366928›Full record

ArticleFrontiers in psychiatry2021

The Impact of Persistent Irritability on the Medication Treatment of Paediatric Attention Deficit Hyperactivity Disorder.

Raman Baweja, Daniel A Waschbusch, William E Pelham, William E Pelham, James G Waxmonsky

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in psychiatry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.1field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 10 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Raman BawejaDepartment of Psychiatry and Behavioral Health, Penn State College of Medicine, Hershey, PA, United States.
Daniel A WaschbuschDepartment of Psychiatry and Behavioral Health, Penn State College of Medicine, Hershey, PA, United States.
William E PelhamCenter of Human Development, University of California, San Diego, San Diego, CA, United States.
William E PelhamCenter for Children and Families Florida International University, Miami, FL, United States.
James G WaxmonskyDepartment of Psychiatry and Behavioral Health, Penn State College of Medicine, Hershey, PA, United States.
Penn State Milton S. Hershey Medical Center · USFlorida Department of Children and Families · USFlorida International University · US

Funding

Research training in substance use prevention: Closing the research-practice gapT32DA039772 · NIDA · ARIZONA STATE UNIVERSITY-TEMPE CAMPUS · PI Cady Berkel, Nancy A. Gonzales · 2015 to 2026
$4.2M
Examining Tolerance to CNS Stimulants in ADDR01MH099030 · NIMH · FLORIDA INTERNATIONAL UNIVERSITY · PI PELHAM, WILLIAM E, SWANSON, JAMES M · 2013 to 2017
$3.3M
A Novel Approach to Stimulant-Induced Weight Suppression and its Impact on GrowthR01MH083692 · NIMH · STATE UNIVERSITY OF NEW YORK AT BUFFALO · PI PELHAM, WILLIAM E, WAXMONSKY, JAMES GAIER · 2009 to 2014
$3.1M
Neural correlates of adult outcomes of childhood ADHD: Affect, reward and controlR01MH101096 · NIMH · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI LADOUCEUR, CECILE D., MOLINA, BROOKE S.G. · 2014 to 2018
$3.0M
Mechanisms of Response to Substance Use Prevention Intervention for Adolescents with ADHDR01DA034731 · NIDA · FLORIDA INTERNATIONAL UNIVERSITY · PI PELHAM, WILLIAM E · 2014 to 2018
$2.9M
Designing a Novel Behavioral Treatment Protocol for Children Characterized by ConR34MH085796 · NIMH · STATE UNIVERSITY OF NEW YORK AT BUFFALO · PI COLES, ERIKA · 2010 to 2012
$648k
A Novel Multimodal Intervention for Children with ADHD and Impaired MoodR34MH080791 · NIMH · STATE UNIVERSITY OF NEW YORK AT BUFFALO · PI WAXMONSKY, JAMES GAIER · 2008 to 2010
$628k
Identifying Children and Teens at Risk for Early Onset Alcohol Use: An Innovative Application of Machine Learning Algorithms to PreventionF31AA026768 · NIAAA · ARIZONA STATE UNIVERSITY-TEMPE CAMPUS · PI PELHAM III, WILLIAM ELLERBE · 2018 to 2019
$88k
NIAAA NIH HHS F31 AA026768NIDA NIH HHS R01 DA034731NIDA NIH HHS T32 DA039772NIMH NIH HHS R01 MH083692NIMH NIH HHS R01 MH099030NIMH NIH HHS R01 MH101096NIMH NIH HHS R34 MH080791NIMH NIH HHS R34 MH085796
6 · The paper itself

Abstract

This study compares the efficacy and tolerability of central nervous system (CNS) stimulants in children with attention deficit hyperactivity disorder (ADHD) with and without prominent irritability (IRR) over the course of 30 months. This is a secondary analysis of a study examining growth patterns in medication naïve children with ADHD subsequently treated with CNS stimulants (predominantly OROS-Methylphenidate, up to 54 mg per day) for 30 months. Participants had to meet full diagnostic criteria for ADHD and been treated with CNS stimulants for under 30 days. Children were classified as IRR if they were rated as

Indexed as

ADHDchildrenCNS stimulantirritabilitymedication

Identifiers

PMID34366928
PMCPMC8333707
OpenAlexW3185931668

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.