Evidence map›Paper›PMID 34366927›Full record

ArticleFrontiers in psychiatry2021

Developmental Alcohol Exposure in Drosophila: Effects on Adult Phenotypes and Gene Expression in the Brain.

Sneha S Mokashi, Vijay Shankar, Rebecca A MacPherson, Rachel C Hannah, Trudy F C Mackay, Robert R H Anholt

Open access · goldAbstract read
In one paragraph

Article in Frontiers in psychiatry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
6.7field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 24 citations in OpenAlex.

  1. Article
  2. Arsenic toxicity in theFrontiers in toxicology · 2025
    Article
  3. Review
  4. Review
  5. Article
  6. Review
  7. Article
  8. Review
  9. iScience · 2023
    Article
  10. Review
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Sneha S MokashiDepartment of Genetics and Biochemistry and Center for Human Genetics, Clemson University, Greenwood, SC, United States.
Vijay ShankarDepartment of Genetics and Biochemistry and Center for Human Genetics, Clemson University, Greenwood, SC, United States.
Rebecca A MacPhersonDepartment of Genetics and Biochemistry and Center for Human Genetics, Clemson University, Greenwood, SC, United States.
Rachel C HannahDepartment of Genetics and Biochemistry and Center for Human Genetics, Clemson University, Greenwood, SC, United States.
Trudy F C MackayDepartment of Genetics and Biochemistry and Center for Human Genetics, Clemson University, Greenwood, SC, United States.
Robert R H AnholtDepartment of Genetics and Biochemistry and Center for Human Genetics, Clemson University, Greenwood, SC, United States.
Center for Human Genetics · USClemson University · US

Funding

Statistical Methods for Gene Regulatory Analysis From Single Cell Genomics DataP20GM139769 · NIGMS · CLEMSON UNIVERSITY · PI MACKAY, TRUDY F. · 2021 to 2025
$10.8M
Genetics of Cocaine Sensitivity in DrosophilaU01DA041613 · NIDA · NORTH CAROLINA STATE UNIVERSITY RALEIGH · PI Robert R. H Anholt, TRUDY F. MACKAY · 2017 to 2026
$4.9M
Genetics of Alcohol Sensitivity in DrosophilaR01AA016560 · NIAAA · NORTH CAROLINA STATE UNIVERSITY RALEIGH · PI ANHOLT, ROBERT R. H, MACKAY, TRUDY F. · 2007 to 2016
$4.0M
Reverse Engineering Quantitative Genetic VariationR01GM128974 · NIGMS · CLEMSON UNIVERSITY · PI ANHOLT, ROBERT R. H, MACKAY, TRUDY F. · 2018 to 2021
$1.9M
NIAAA NIH HHS R01 AA016560NIDA NIH HHS U01 DA041613NIGMS NIH HHS P20 GM139769NIGMS NIH HHS R01 GM128974
6 · The paper itself

Abstract

Fetal alcohol exposure can lead to developmental abnormalities, intellectual disability, and behavioral changes, collectively termed fetal alcohol spectrum disorder (FASD). In 2015, the Centers for Disease Control found that 1 in 10 pregnant women report alcohol use and more than 3 million women in the USA are at risk of exposing their developing fetus to alcohol.

Indexed as

behavioral geneticsfetal alcohol spectrum disorderinteraction networksmodel organismsingle cell RNA sequencingtranscriptomics

Identifiers

PMID34366927
PMCPMC8341641
OpenAlexW3185835264

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.