Evidence map›Paper›PMID 34366824›Full record

ArticleFrontiers in aging neuroscience2021

The Dynamic Motor Control Index as a Marker of Age-Related Neuromuscular Impairment.

Ashley N Collimore, Ashlyn J Aiello, Ryan T Pohlig, Louis N Awad

2 registry-linked trialsAbstract read
In one paragraph

Article in Frontiers in aging neuroscience, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07212608 nacompletednot on this mapstarted 2022, after this paper: background citation

Wearable Gait Interventions for Augmenting Paretic Propulsion: Towards Personalized Post-Stroke Gait Rehabilitation

TypeinterventionalSponsorBoston University Charles River CampusRan2022 to 2025Enrolled22ConditionsStrokeArmsSoft robotic exosuit, Propulsion neuroprosthesis
NCT07218094 naenrolling by invitationnot on this mapstarted 2025, after this paper: background citation

Neuromechanical Mechanisms of Exosuit-assisted Gait Rehabilitation After Stroke

TypeinterventionalSponsorBoston University Charles River CampusRan2025 to 2027Enrolled22ConditionsStrokeArmsWalking with robotic ankle assistance
3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Ashley N CollimoreNeuromotor Recovery Laboratory, Department of Physical Therapy, College of Health and Rehabilitation Sciences: Sargent College, Boston University, Boston, MA, United States.
Ashlyn J AielloNeuromotor Recovery Laboratory, Department of Physical Therapy, College of Health and Rehabilitation Sciences: Sargent College, Boston University, Boston, MA, United States.
Ryan T PohligBiostatistics Core Facility, University of Delaware, Newark, DE, United States.
Louis N AwadNeuromotor Recovery Laboratory, Department of Physical Therapy, College of Health and Rehabilitation Sciences: Sargent College, Boston University, Boston, MA, United States.

Funding

SCH: Multimodal,Task-Aware Movement Assessment and Control: Clinic to HomeR01AG067394 · NIA · BOSTON UNIVERSITY (CHARLES RIVER CAMPUS) · PI AWAD, LOUIS N, TRON, ROBERTO · 2019 to 2022
$1.2M
NIA NIH HHS R01 AG067394
6 · The paper itself

Abstract

Biomarkers that can identify age-related decline in walking function have potential to promote healthier aging by triggering timely interventions that can mitigate or reverse impairments. Recent evidence suggests that changes in neuromuscular control precede changes in walking function; however, it is unclear which measures are best suited for identifying age-related changes. In this study, non-negative matrix factorization of electromyography data collected during treadmill walking was used to calculate two measures of the complexity of muscle co-activations during walking for 36 adults: (1) the number of muscle synergies and (2) the dynamic motor control index. Study participants were grouped into young (18-35 years old), young-old (65-74 years old), and old-old (75+ years old) subsets. We found that the dynamic motor control index [χ

Indexed as

aginggaitmotor controlmuscle activitywalking

Identifiers

PMID34366824
PMCPMC8339561

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.