Evidence map›Paper›PMID 34366682›Full record

ArticleJournal of blood medicine2021

Incidence and Risk Factors of Thrombocytopenia in Neonates Admitted with Surgical Disorders to Neonatal Intensive Care Unit of Tikur Anbessa Specialized Hospital: A One-Year Observational Prospective Cohort Study from a Low-Income Country.

Hana Abebe Gebreselassie, Hanna Getachew, Amezene Tadesse, Tihitena Negussie Mammo, Woubedel Kiflu, Fisseha Temesgen, Belachew Dejene

Open access · goldAbstract read
In one paragraph

Article in Journal of blood medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 2 pooled it
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 2 syntheses or guidelines pooled it, 15 citations in OpenAlex.

  1. Platelet transfusion thresholds for thrombocytopenic infants.The Cochrane database of systematic reviews · 2026
    Pooled it
  2. Pooled it
  3. Efficacy and Safety of Recombinant Human Thrombopoietin (rhTPO) on Coagulation Function and Inflammatory Factors in the Treatment of Patients with Sepsis-Related Thrombocytopenia.Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis
    Trial
  4. Article
  5. Article
  6. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Hana Abebe GebreselassieSt. Paul's Hospital Millennium Medical College, Department of Surgery, Addis Ababa, Ethiopia.
Hanna GetachewAddis Ababa University School of Medicine, Department of Surgery, Paediatrics Surgery Unit, Addis Ababa, Ethiopia.
Amezene TadesseAddis Ababa University School of Medicine, Department of Surgery, Paediatrics Surgery Unit, Addis Ababa, Ethiopia.
Tihitena Negussie MammoAddis Ababa University School of Medicine, Department of Surgery, Paediatrics Surgery Unit, Addis Ababa, Ethiopia.
Woubedel KifluAddis Ababa University School of Medicine, Department of Surgery, Paediatrics Surgery Unit, Addis Ababa, Ethiopia.
Fisseha TemesgenAddis Ababa University School of Medicine, Department of Surgery, Paediatrics Surgery Unit, Addis Ababa, Ethiopia.
Belachew DejeneAddis Ababa University School of Medicine, Department of Surgery, Paediatrics Surgery Unit, Addis Ababa, Ethiopia.
Addis Ababa University · ETSt. Paul's Hospital Millennium Medical College · ET

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThrombocytopenia is one of the most common hematologic disorders affecting neonates admitted to the neonatal intensive care unit. The aim of this study was to determine the incidence and associated risk factors of neonatal thrombocytopenia in neonates admitted with surgical disorders.

methodsAn observational prospective cohort study was conducted and all neonates admitted to neonatal intensive care unit of Tikur Anbessa Specialized Hospital with surgical disorders were included. Data were collected using a checklist and analyzed by SPSS version 23. Chi square test and independent sample

resultsA total of 210 neonates were included in the study, out of which 56.2% were males. The incidence of thrombocytopenia was 55.8%. Among neonates with thrombocytopenia, 90.9% had late onset thrombocytopenia and half were in the severe range (<50,000/µL). The presence of sepsis (P = 0.000) and atresia (P = 0.000) were found to be significantly associated with the development of thrombocytopenia. The mean non feeding hours were found to be significantly longer for patients with thrombocytopenia (t [199], 5.81, P = 0.000).

conclusionThe incidence of thrombocytopenia is high in our institution. Prevention methods towards neonatal sepsis should be given due emphasis.

Indexed as

incidencerisk factorsthrombocytopenia

Identifiers

PMID34366682
PMCPMC8335549
OpenAlexW3187814406

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.