Evidence map›Paper›PMID 34366660›Full record

ArticleDrugs & therapy perspectives : for rational drug selection and use2021

Adverse events related to COVID-19 vaccines: the need to strengthen pharmacovigilance monitoring systems.

Sunil Shrestha, Januka Khatri, Sujyoti Shakya, Krisha Danekhu, Asmita Priyadarshini Khatiwada, Ranjit Sah, Bhuvan Kc, Vibhu Paudyal, Saval Khanal, Alfonso J Rodriguez-Morales

Open access · bronzeAbstract read
In one paragraph

Article in Drugs & therapy perspectives : for rational drug selection and use, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 2 pooled it
3.2field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 2 syntheses or guidelines pooled it, 54 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
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  6. Newer emerging SARS-COV2 variant: Omicron EG.5.Annals of medicine and surgery (2012) · 2023
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  9. Observational
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  15. Article
  16. Reactogenicity to COVID-19 vaccination in the United States of America.Clinical and experimental vaccine research · 2022
    Article
  17. Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 7 institutions in 6 countries.

Sunil ShresthaSchool of Pharmacy, Monash University Malaysia, Jalan Lagoon Selatan, 47500 Bandar Sunway, Selangor Malaysia.ORCID 0000-0002-9174-7120
Januka KhatriDepartment of Pharmacy, School of Science, Kathmandu University, Dhulikhel, Kavre Nepal.
Sujyoti ShakyaDepartment of Pharmaceutical and Health Service Research, Nepal Health Research and Innovation Foundation, Lalitpur, Nepal.
Krisha DanekhuDepartment of Pharmaceutical and Health Service Research, Nepal Health Research and Innovation Foundation, Lalitpur, Nepal.
Asmita Priyadarshini KhatiwadaDepartment of Pharmaceutical and Health Service Research, Nepal Health Research and Innovation Foundation, Lalitpur, Nepal.
Ranjit SahInstitute of Medicine, Tribhuvan University Teaching Hospital, Kathmandu, Nepal.
Bhuvan KcSchool of Pharmacy, Monash University Malaysia, Jalan Lagoon Selatan, 47500 Bandar Sunway, Selangor Malaysia.
Vibhu PaudyalSchool of Pharmacy, College of Medical and Dental Sciences, University of Birmingham, Birmingham, United Kingdom.
Saval KhanalDivision of Health Sciences, Warwick Medical School, University of Warwick, Coventry, United Kingdom.
Alfonso J Rodriguez-MoralesGrupo de Investigación Biomedicina, Faculty of Medicine, Fundacion Universitaria Autonoma de Las Americas, Pereira, Risaralda Colombia.
Nepal Development Research Institute · NPMonash University Malaysia · MYKathmandu University · NPTribhuvan University Teaching Hospital · NPUniversidad Científica del Sur · PEUniversity of Birmingham · GBUniversity of Warwick · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Coronavirus disease 2019 (COVID-19) is an infectious disease caused by a new species of β-coronavirus genus named severe acute respiratory syndrome coronavirus 2. The COVID-19 pandemic, which started in late 2019 and continues as at mid-2021, has caused enormous damage to health and lives globally. The urgent public health need has led to the development of vaccines against COVID-19 in record-breaking time. The COVID-19 vaccines have been widely rolled out for the masses by many countries following approval for emergency use by the World Health Organization and regulatory agencies in many countries. In addition, several COVID-19 vaccine candidates are undergoing clinical trials. However, myths, fears, rumors, and misconceptions persist, particularly in regard to adverse events. In this commentary, we describe the adverse events associated with COVID-19 vaccines and discuss why it is essential to have a functional adverse event monitoring system in this context.

Identifiers

PMID34366660
PMCPMC8327058
OpenAlexW3185595999

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.