Evidence map›Paper›PMID 34366605›Full record

ReviewWorld journal of gastroenterology2021

Viral infections in inflammatory bowel disease: Tips and tricks for correct management.

Vincenzo Craviotto, Federica Furfaro, Laura Loy, Alessandra Zilli, Laurent Peyrin-Biroulet, Gionata Fiorino, Silvio Danese, Mariangela Allocca

Open access · greenAbstract readReview
In one paragraph

Review in World journal of gastroenterology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 23 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Vincenzo CraviottoHumanitas Clinical and Research Center, IRCCS, Rozzano 20089, Milano, Italy.
Federica FurfaroHumanitas Clinical and Research Center, IRCCS, Rozzano 20089, Milano, Italy.
Laura LoyHumanitas Clinical and Research Center, IRCCS, Rozzano 20089, Milano, Italy.
Alessandra ZilliHumanitas Clinical and Research Center, IRCCS, Rozzano 20089, Milano, Italy.
Laurent Peyrin-BirouletDepartment of Hepato-Gastroenterology and Inserm U954, University Hospital of Nancy, Lorraine University, Nancy 54511, France.
Gionata FiorinoHumanitas Clinical and Research Center, IRCCS, Rozzano 20089, Milano, Italy.
Silvio DaneseHumanitas Clinical and Research Center, IRCCS, Rozzano 20089, Milano, Italy.
Mariangela AlloccaHumanitas Clinical and Research Center, IRCCS, Rozzano 20089, Milano, Italy.
Humanitas University · ITInserm · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Over the past decades, the treatment of inflammatory bowel diseases (IBD) has become more targeted, anticipating the use of immune-modifying therapies at an earlier stage. This top-down approach has been correlated with favorable short and long-term outcomes, but it has also brought with it concerns regarding potential infectious complications. This large IBD population treated with immune-modifying therapies, especially if combined, has an increased risk of severe infections, including opportunistic infections that are sustained by viral, bacterial, parasitic, and fungal agents. Viral infections have emerged as a focal safety concern in patients with IBD, representing a challenge for the clinician: they are often difficult to diagnose and are associated with significant morbidity and mortality. The first step is to improve effective preventive strategies, such as applying vaccination protocols, adopt adequate prophylaxis and educate patients about potential risk factors. Since viral infections in immunosuppressed patients may present atypical signs and symptoms, the challenges for the gastroenterologist are to suspect, recognize and diagnose such complications. Appropriate treatment of common viral infections allows us to minimize their impact on disease outcomes and patients' lives. This practical review supports this standard of care to improve knowledge in this subject area.

Indexed as

ColitisInflammatory Bowel DiseasesOpportunistic InfectionsVirus DiseasesHumansImmunocompromised HostCrohn’s diseaseInflammatory bowel diseasesOpportunistic infectionsStandard of careUlcerative colitisViral infections

Identifiers

PMID34366605
PMCPMC8316900
OpenAlexW3183536990

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.