Evidence map›Paper›PMID 34366603›Full record

ReviewRare metals2022

Stimuli-responsive nanocarriers for bacterial biofilm treatment.

Meng Ding, Wei Zhao, Ling-Jie Song, Shi-Fang Luan

Open access · bronzeAbstract readReview
In one paragraph

Review in Rare metals, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
3.9field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 80 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 4 institutions in 2 countries.

Meng Ding *State Key Laboratory of Polymer Physics and Chemistry, Changchun Institute of Applied Chemistry, Chinese of Academy, Changchun, 130022 China.
Wei Zhao *State Key Laboratory of Polymer Physics and Chemistry, Changchun Institute of Applied Chemistry, Chinese of Academy, Changchun, 130022 China.
Ling-Jie SongState Key Laboratory of Polymer Physics and Chemistry, Changchun Institute of Applied Chemistry, Chinese of Academy, Changchun, 130022 China.ORCID 0000-0002-7126-3778
Shi-Fang LuanState Key Laboratory of Polymer Physics and Chemistry, Changchun Institute of Applied Chemistry, Chinese of Academy, Changchun, 130022 China.ORCID 0000-0002-7660-9010
Changchun Institute of Applied Chemistry · CNThe Medical Device (United Kingdom) · GBUniversity of Science and Technology of China · CNYantai University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

abstractBacterial biofilm infections have been threatening the human's life and health globally for a long time because they typically cause chronic and persistent infections. Traditional antibiotic therapies can hardly eradicate biofilms in many cases, as biofilms always form a robust fortress for pathogens inside, inhibiting the penetration of drugs. To address the issues, many novel drug carriers emerged as promising strategies for biofilm treatment. Among them, stimuli-responsive nanocarriers have attracted much attentions for their intriguing physicochemical properties, such as tunable size, shape and surface chemistry, especially smart drug release characteristic. Based on the microenvironmental difference between biofilm infection sites and normal tissue, many stimuli, such as bacterial products accumulating in biofilms (enzymes, glutathione, etc.), lower pH and higher H 摘要: , , 。 , , 。 , , 。 , -, , , , 。 , , (, ), pHH GRAPHIC ABSTRACT:

Indexed as

BactericidalBiofilm eradicationDrug releaseNanocarriersStimuli responsive

Identifiers

PMID34366603
PMCPMC8333162
OpenAlexW3190912758

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.