Evidence map›Paper›PMID 34366494›Full record

ArticleAngewandte Chemie (Weinheim an der Bergstrasse, Germany)2020

Ultra-fast cycling for multiplexed cellular fluorescence imaging.

Jina Ko, Juhyun Oh, Maaz S Ahmed, Jonathan C T Carlson, Ralph Weissleder

Abstract read
In one paragraph

Article in Angewandte Chemie (Weinheim an der Bergstrasse, Germany), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Review
  2. Review
  3. Live Organoid Cyclic Imaging.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024
    Article
  4. Article
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jina KoCenter for Systems Biology, Massachusetts General Hospital Research Institute, Boston, MA 02114.ORCID 0000-0002-4941-4234
Juhyun OhCenter for Systems Biology, Massachusetts General Hospital Research Institute, Boston, MA 02114.ORCID 0000-0002-4492-6978
Maaz S AhmedCenter for Systems Biology, Massachusetts General Hospital Research Institute, Boston, MA 02114.ORCID 0000-0001-9558-5790
Jonathan C T CarlsonCenter for Systems Biology, Massachusetts General Hospital Research Institute, Boston, MA 02114.ORCID 0000-0003-4139-9057
Ralph WeisslederCenter for Systems Biology, Massachusetts General Hospital Research Institute, Boston, MA 02114.ORCID 0000-0003-0828-4143

Funding

The role of microvesicles in giloma virotherapyP01CA069246 · NCI · MASSACHUSETTS GENERAL HOSPITAL · PI CHAREST, ALAIN · 1996 to 2021
$30.9M
Training Grant in Molecular Imaging Research (MGH/HMS)T32CA079443 · NCI · MASSACHUSETTS GENERAL HOSPITAL · PI WEISSLEDER, MD, PHD, RALPH · 2000 to 2025
$10.1M
Smartphone for molecular cancer diagnostic in AfricaUH3CA202637 · NCI · MASSACHUSETTS GENERAL HOSPITAL · PI CHABNER, BRUCE ALLAN, WEISSLEDER, MD, PHD, RALPH · 2018 to 2020
$2.9M
Imaging tumor associated macrophage (TAM) functionR01CA206890 · NCI · MASSACHUSETTS GENERAL HOSPITAL · PI PITTET, MIKAEL, WEISSLEDER, MD, PHD, RALPH · 2017 to 2021
$1.9M
NCI NIH HHS P01 CA069246NCI NIH HHS R01 CA206890NCI NIH HHS T32 CA079443NCI NIH HHS UH3 CA202637
6 · The paper itself

Abstract

Rapid analysis of single and scant cell populations is essential in modern diagnostics, yet existing methods are often limited and slow. Here we describe an ultra-fast, highly efficient cycling method for the analysis of single cells based on unique linkers for tetrazine (Tz) /

Indexed as

bioorthogonal chemistrycancerclick chemistrydiagnostic Wileyenergy transferfluorescencefluorescent probesquenchingtetrazinetetrazines

Identifiers

PMID34366494
PMCPMC8340598

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.