Trial reportJournal of perinatology : official journal of the California Perinatal Association2021
Randomized controlled trial of the "WISER" intervention to reduce healthcare worker burnout.
Trial report in Journal of perinatology : official journal of the California Perinatal Association, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 33 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Web-based Implementation for the Science of Enhancing Resilience Study
The WISER Study: Web Based Methods for Enhancing Resilience
Who cites it
33 citing papers in PubMed, 4 syntheses or guidelines pooled it, 57 citations in OpenAlex.
- Interventions to reduce empathy-based stress and enhance compassionate care in mental health wards: a systematic review.BMC health services research · 2025Pooled it
- Digital resilience interventions for healthcare workers: a systematic review.Frontiers in psychiatry · 2025Pooled it
- The effectiveness of e-mental health interventions on stress, anxiety, and depression among healthcare professionals: a systematic review and meta-analysis.Systematic reviews · 2024Pooled it
- Individual-level interventions for reducing occupational stress in healthcare workers.The Cochrane database of systematic reviews · 2023Pooled it
- Feasibility of a tailored, combined intervention with mind-body elements to prevent burnout in healthcare professionals (LAGOM) in a mixed-methods multicenter single-arm trial.Scientific reports · 2025Trial
- "WISER" intervention to reduce healthcare worker burnout - 1 year follow up.Journal of perinatology : official journal of the California Perinatal Association · 2024Trial
- Well-Being Outcomes of Health Care Workers After a 5-Hour Continuing Education Intervention: The WELL-B Randomized Clinical Trial.JAMA network open · 2024Trial
- Reducing intrusive memories after trauma via an imagery-competing task intervention in COVID-19 intensive care staff: a randomised controlled trial.Translational psychiatry · 2023Trial
- Efficacy of Transcendental Meditation to Reduce Stress Among Health Care Workers: A Randomized Clinical Trial.JAMA network open · 2022Trial
- Effectiveness of a bite-sized web-based intervention to improve healthcare worker wellbeing: A randomized clinical trial of WISER.Frontiers in public health · 2022Trial
- Promising Practices in Implementing Interventions for Health Worker Burnout: Preventing and Addressing Burnout.Healthcare management forum · 2026Article
- Assessment of Clinician Well-Being Using a Biometric-Informed Coaching Platform.JAMA network open · 2026Article
- The Human Face of Digitalization in Healthcare: A Mixed-Methods Study on the Relationship Between Emotional Intelligence and Burnout.Behavioral sciences (Basel, Switzerland) · 2025Article
- Learning Health System study designs for the evaluation of workforce interventions to cultivate eudaimonia (flourishing).Learning health systems · 2025Article
- "Exploring Psychosocial Interventions to Improve Mental Health Outcomes Among Healthcare Workers": Scoping Review.Journal of multidisciplinary healthcare · 2025Review
- Protocol of randomized-controlled trial to examine the effectiveness of three different interventions to reduce healthcare provider burnout.BMC health services research · 2024Article
- Article
- Burnout and turnover risks for healthcare workers in the United States: downstream effects from moral injury exposure.Scientific reports · 2024Article
- HELLO: a protocol for a cluster randomized controlled trial to enhance interpersonal relationships and team cohesion among ICU healthcare professionals.Intensive care medicine experimental · 2024Article
- Association of Shift-Level Organizational Factors with Nosocomial Infection in the Neonatal Intensive Care Unit.Journal of pediatrics. Clinical practice · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
20 authors at 11 institutions in 1 country.
Funding
Abstract
objectiveTest web-based implementation for the science of enhancing resilience (WISER) intervention efficacy in reducing healthcare worker (HCW) burnout.
designRCT using two cohorts of HCWs of four NICUs each, to improve HCW well-being (primary outcome: burnout). Cohort 1 received WISER while Cohort 2 acted as a waitlist control.
resultsCohorts were similar, mostly female (83%) and nurses (62%). In Cohorts 1 and 2 respectively, 182 and 299 initiated WISER, 100 and 176 completed 1-month follow-up, and 78 and 146 completed 6-month follow-up. Relative to control, WISER decreased burnout (-5.27 (95% CI: -10.44, -0.10), p = 0.046). Combined adjusted cohort results at 1-month showed that the percentage of HCWs reporting concerning outcomes was significantly decreased for burnout (-6.3% (95%CI: -11.6%, -1.0%); p = 0.008), and secondary outcomes depression (-5.2% (95%CI: -10.8, -0.4); p = 0.022) and work-life integration (-11.8% (95%CI: -17.9, -6.1); p < 0.001). Improvements endured at 6 months.
conclusionWISER appears to durably improve HCW well-being. CLINICAL TRIALS NUMBER: NCT02603133; https://clinicaltrials.gov/ct2/show/NCT02603133.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.