Evidence map›Paper›PMID 34366333›Full record

ArticleJournal of Alzheimer's disease : JAD2021

Neuropsychological Predictors of Severe Functional Dependency in a Multiethnic Community Cohort of Individuals with Alzheimer's Disease.

Jasmine Cárcamo, Anton J Kociolek, Kayri K Fernández, Yian Gu, Carolyn W Zhu, Yaakov Stern, Stephanie Cosentino

Open access · greenAbstract readLetter
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of Alzheimer's disease : JAD, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Jasmine CárcamoTaub Institute for Research on Alzheimer's Disease and the Aging Brain, Vagelos College of Physicians and Surgeons, Columbia University, New York, NY, USA.
Anton J KociolekTaub Institute for Research on Alzheimer's Disease and the Aging Brain, Vagelos College of Physicians and Surgeons, Columbia University, New York, NY, USA.
Kayri K FernándezTaub Institute for Research on Alzheimer's Disease and the Aging Brain, Vagelos College of Physicians and Surgeons, Columbia University, New York, NY, USA.
Yian GuTaub Institute for Research on Alzheimer's Disease and the Aging Brain, Vagelos College of Physicians and Surgeons, Columbia University, New York, NY, USA.
Carolyn W ZhuBrookdale Department of Geriatrics and Palliative Medicine, Icahn School of Medicine a Mount Sinai, New York, NY, USA.
Yaakov SternTaub Institute for Research on Alzheimer's Disease and the Aging Brain, Vagelos College of Physicians and Surgeons, Columbia University, New York, NY, USA.
Stephanie CosentinoTaub Institute for Research on Alzheimer's Disease and the Aging Brain, Vagelos College of Physicians and Surgeons, Columbia University, New York, NY, USA.
Columbia University · USJames J. Peters VA Medical Center · US

Funding

Research Education CoreP30AG066462 · NIA · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI Miguel Arce · 2020 to 2026
$30.1M
PREDICTORS OF SEVERITY IN ALZHEIMERS DISEASER01AG007370 · NIA · COLUMBIA UNIV NEW YORK MORNINGSIDE · PI STERN, YAAKOV · 1989 to 2021
$16.6M
NIA NIH HHS P30 AG066462NIA NIH HHS R01 AG007370
6 · The paper itself

Abstract

To assess the predictive value of neuropsychological tests for severe dependency in Alzheimer's disease as defined by the Equivalent Institutional Care Rating Scale, in a multiethnic, community cohort. The sample included 146 elders from the Predictors 3 cohort. Cox proportional hazard models tested the predictive value of each neuropsychological test at baseline on relative risk of meeting severe dependency. Higher semantic processing and memory test scores at baseline were associated with lower risk of meeting severe dependency in the adjusted Cox models. The integrity of semantic processing and memory abilities in dementia appears to predict time to severe functional dependency.

Indexed as

Physical Functional PerformancePredictive Value of TestsResidence CharacteristicsAged, 80 and overAlzheimer DiseaseCognition DisordersDisease ProgressionFemaleHumansMaleNeuropsychological TestsProspective StudiesAlzheimer’s diseasecognitiondementiamemoryneuropsychological tests

Identifiers

PMID34366333
PMCPMC10131178
OpenAlexW3188840612

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.