Evidence map›Paper›PMID 34365985›Full record

ArticleDevelopment and psychopathology2021

The centrality of temperament to the research domain criteria (RDoC): The earliest building blocks of psychopathology.

Brendan Ostlund, Sarah Myruski, Kristin Buss, Koraly E Pérez-Edgar

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In one paragraph

Article in Development and psychopathology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Neural correlates of child temperament: The role of brain network connectivity in psychopathology risk.Journal of child psychology and psychiatry, and allied disciplines · 2026
    Article
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  11. When the World Pivots: Changes in Infant Negative Affect Trajectories Following the Onset of the COVID-19 Pandemic.Infancy : the official journal of the International Society on Infant Studies
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Brendan OstlundDepartment of Psychology, The Pennsylvania State University, University Park, US.ORCID 0000-0002-2166-7707
Sarah MyruskiDepartment of Psychology, The Pennsylvania State University, University Park, US.
Kristin BussDepartment of Psychology, The Pennsylvania State University, University Park, US.ORCID 0000-0001-5692-6126
Koraly E Pérez-EdgarDepartment of Psychology, The Pennsylvania State University, University Park, US.

Funding

Emerging relations between attention and negative affect in the first two years of lifeR01MH109692 · NIMH · PENNSYLVANIA STATE UNIVERSITY, THE · PI BUSS, KRISTIN A, LOBUE, VANESSA · 2016 to 2020
$4.5M
Biobehavioral Trajectories of Social Anxiety from Early to Middle AdolescenceR01MH114974 · NIMH · PENNSYLVANIA STATE UNIVERSITY, THE · PI BUSS, KRISTIN A · 2018 to 2022
$4.2M
NIMH NIH HHS R01 MH109692NIMH NIH HHS R01 MH114974
6 · The paper itself

Abstract

The research domain criteria (RDoC) is an innovative approach designed to explore dimensions of human behavior. The aim of this approach is to move beyond the limits of psychiatric categories in the hope of aligning the identification of psychological health and dysfunction with clinical neuroscience. Despite its contributions to adult psychopathology research, RDoC undervalues ontogenetic development, which circumscribes our understanding of the etiologies, trajectories, and maintaining mechanisms of psychopathology risk. In this paper, we argue that integrating temperament research into the RDoC framework will advance our understanding of the mechanistic origins of psychopathology beginning in infancy. In illustrating this approach, we propose the incorporation of core principles of temperament theories into a new "life span considerations" subsection as one option for infusing development into the RDoC matrix. In doing so, researchers and clinicians may ultimately have the tools necessary to support emotional development and reduce a young child's likelihood of psychological dysfunction beginning in the first years of life.

Indexed as

Mental DisordersNeurosciencesChildEmotionsHumansPsychopathologyTemperamentdevelopmental psychopathologyearly childhoodinfancyresearch domain criteria (RDoC)temperament

Identifiers

PMID34365985
PMCPMC10039756

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Textfull text, public
LicenceCC BY
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.