Evidence map›Paper›PMID 34365903›Full record

ArticleBioengineered2021

Pseudopodium enriched atypical kinase 1(PEAK1) promotes invasion and of melanoma cells by activating JAK/STAT3 signals.

Min Pan, Xiaohui Yin, Yi-Chuan Huang

Open access · goldAbstract read
In one paragraph

Article in Bioengineered, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.6field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Min PanDepartment of Dermatology, The Affiliated Hospital of Qingdao University, Qingdao, China.
Xiaohui YinDepartment of Dermatology, Qingdao Women and Children's Hospital, Qingdao, China.
Yi-Chuan HuangDepartment of Otolaryngology, The Affiliated Hospital of Qingdao University, Qingdao, China.ORCID 0000-0001-7966-4421
Qingdao University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pseudopodium enriched atypical kinase 1(PEAK1) is a non-receptor tyrosine kinase, which is enriched in the pseudopodia of migrating cells and plays an important role in regulating cell migration and proliferation. In the study, we investigate the therapeutic effect of PEAK1 on melanoma cells

Indexed as

MelanomaProtein-Tyrosine KinasesAnimalsCell Line, TumorFemaleHumansJanus KinasesMiceMice, NudeNeoplasm InvasivenessNeoplasm MetastasisSignal TransductionSTAT3 Transcription FactorJanus KinasesPEAK1 protein, humanProtein-Tyrosine KinasesSTAT3 protein, humanSTAT3 Transcription FactorJAK/STAT3 signalsMelanomametastasispseudopodium enriched atypical kinase

Identifiers

PMID34365903
PMCPMC8806756
OpenAlexW3192325693

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.