Evidence map›Paper›PMID 34365780›Full record

ArticleTurkish journal of medical sciences2022

Survival of biological therapeutics in psoriasis: retrospective analysis of 3-years data in a Turkish registry, PSORTAKSIS.

Kemal Özyurt, Gökmen Zararsız, Ragıp Ertaş, Ahu Cephe, Ömer Kutlu, Ömer Faruk Elmas, Muhammed Reşat Akkuş, Fatma Nur Kutlu, Mustafa Atasoy

Open access · bronzeAbstract read
In one paragraph

Article in Turkish journal of medical sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact, top 85% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it, 0 citations in OpenAlex.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 2 countries.

Kemal ÖzyurtDepartment of Dermatology and Venereology, Medicine Faculty, Ahi Evran University, Kırşehir, Turkey.
Gökmen ZararsızERFARMA, Personalized Medicine and Advanced Analytics Research Group, Erciyes University, Kayseri, Turkey.Department of Biostatistics, Faculty of Medicine, Erciyes University Kayseri, Turkey.
Ragıp ErtaşDepartment of Dermatology and Venereology, Kayseri City Hospital, Health Science University, Kayseri, Turkey.
Ahu CepheERFARMA, Personalized Medicine and Advanced Analytics Research Group, Erciyes University, Kayseri, Turkey.
Ömer KutluDepartment of Dermatology and Venereology, School of Medicine, Tokat Gaziosmanpaşa University, Tokat, Turkey.
Ömer Faruk ElmasDepartment of Dermatology and Venereology, School of Medicine, Kırıkkale University, Kırıkkale, Turkey.
Muhammed Reşat AkkuşDepartment of Dermatology and Venereology, Kayseri City Hospital, Health Science University, Kayseri, Turkey.
Fatma Nur KutluDepartment of Dermatology and Venereology, Kayseri City Hospital, Health Science University, Kayseri, Turkey.
Mustafa AtasoyDepartment of Dermatology and Venereology, Kayseri City Hospital, Health Science University, Kayseri, Turkey.
Kayseri Eğitim ve Araştırma Hastanesi · TRErciyes University · TRAhi Evran University · TRTokat Gaziosmanpaşa Üniversitesi · TRUniversity Dermatology · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTPSORTAKSIS is a psoriasis registry, which is used for follow-up of patients in Kayseri City Education and Research Hospital, Dermatology Clinic since 2016 in Turkey. PSORTAKSIS includes demographic data, follow-up clinical findings, laboratory output, and treatment information of patients. Here, drug survivals of biologic therapeutics (BT) according to three-year data of PSORTAKSIS will be presented.

methodsDrug survival of BT in PSORTAKSIS was analyzed from 2016 to March 2019.

results158 patients (111 of them BT-naive) with psoriasis under BT were enrolled in the current study. Drug survival analysis of patients with ongoing BT (158 treatment periods) revealed mean survival time as 15.49 months for ustekinumab, 15.37 months for adalimumab, 14.00 months for etanercept, 5 months for infliximab, and 4.59 months for secukinumab. The differences between drug survivals of BT were statistically significant (log-rank test, χ2 = 79.915, p < 0.0001).

Indexed as

Biological TherapyPsoriasisHumansRegistriesRetrospective StudiesTurkeyUstekinumabUstekinumabanti-TNFdrug survivalPsoriasispsoriasis registrysecukinumabustekinumab

Identifiers

PMID34365780
PMCPMC10734864
OpenAlexW3192966264

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.