Evidence map›Paper›PMID 34365550›Full record

ArticleLasers in medical science2022

Dermabrasion combined with photodynamic therapy: a new option for the treatment of non-melanoma skin cancer.

Nianzhou Yu, Xi Luo, Tianhong Wei, Qian Zhang, Jing Yu, Lisha Wu, Juan Su, Mingliang Chen, Kai Huang, Fangfang Li and 7 more

Abstract readMulticenter Study
PubMed Publisher
In one paragraph

Article in Lasers in medical science, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 6 institutions in 2 countries.

Nianzhou YuDepartment of Dermatology, Hunan Engineering Research Center of Skin Health and Disease, Hunan Key Laboratory of Skin Cancer and Psoriasis, Xiangya Hospital, Central South University, 87 Xiangya Road, Kaifu District, Changsha, Hunan Province, China.
Xi LuoDepartment of Dermatology, Shanghai Dermatology Hospital, Shanghai, 200443, China.
Tianhong WeiDepartment of UltrasoundXiangya Hospital, Central South University, Changsha, 410008, Hunan, China.
Qian ZhangDepartment of Dermatologic Surgery, Hospital of Dermatology, Chinese Academy of Medical Sciences and Peking Union Medical College, Nanjing, China.
Jing YuInstitute of Clinical Pharmacology, Hunan Key Laboratory of Pharmacogenetics, Central South University, 111 Xiangya Road, Changsha, 410078, Hunan, China.
Lisha WuDepartment of Dermatology, Hunan Engineering Research Center of Skin Health and Disease, Hunan Key Laboratory of Skin Cancer and Psoriasis, Xiangya Hospital, Central South University, 87 Xiangya Road, Kaifu District, Changsha, Hunan Province, China.
Juan SuDepartment of Dermatology, Hunan Engineering Research Center of Skin Health and Disease, Hunan Key Laboratory of Skin Cancer and Psoriasis, Xiangya Hospital, Central South University, 87 Xiangya Road, Kaifu District, Changsha, Hunan Province, China.
Mingliang ChenDepartment of Dermatology, Hunan Engineering Research Center of Skin Health and Disease, Hunan Key Laboratory of Skin Cancer and Psoriasis, Xiangya Hospital, Central South University, 87 Xiangya Road, Kaifu District, Changsha, Hunan Province, China.
Kai HuangDepartment of Dermatology, Hunan Engineering Research Center of Skin Health and Disease, Hunan Key Laboratory of Skin Cancer and Psoriasis, Xiangya Hospital, Central South University, 87 Xiangya Road, Kaifu District, Changsha, Hunan Province, China.
Fangfang LiDepartment of Dermatology, Hunan Engineering Research Center of Skin Health and Disease, Hunan Key Laboratory of Skin Cancer and Psoriasis, Xiangya Hospital, Central South University, 87 Xiangya Road, Kaifu District, Changsha, Hunan Province, China.
Yang XieDepartment of Dermatology, The 3rd Affiliated Hospital of Sun Yat-Sen University, 600 Tianhe Road, Guangzhou, 510630, Guangdong, China.
Fang FangDepartment of UltrasoundXiangya Hospital, Central South University, Changsha, 410008, Hunan, China.
Liang ZhangDepartment of Dermatology, Wuhan First People's Hospital, Wuhan, 430022, Hubei, China.
Renliang HeDepartment of Dermatologic Surgery, Dermatology Hospital of Southern Medical University, Guangzhou, 510091, Guangdong, China.
Xiang ChenDepartment of Dermatology, Hunan Engineering Research Center of Skin Health and Disease, Hunan Key Laboratory of Skin Cancer and Psoriasis, Xiangya Hospital, Central South University, 87 Xiangya Road, Kaifu District, Changsha, Hunan Province, China. chenxiangck@126.com.
Shuang ZhaoDepartment of Dermatology, Hunan Engineering Research Center of Skin Health and Disease, Hunan Key Laboratory of Skin Cancer and Psoriasis, Xiangya Hospital, Central South University, 87 Xiangya Road, Kaifu District, Changsha, Hunan Province, China. shuangxy@csu.edu.cn.ORCID http://orcid.org/0000-0001-7081-6177
WenBo BuDepartment of Dermatologic Surgery, Hospital of Dermatology, Chinese Academy of Medical Sciences and Peking Union Medical College, Nanjing, China. buwenbo@163.com.
Central South University · CNChinese Academy of Medical Sciences & Peking Union Medical College · CNShanghai Stomatological Hospital · CNSouthern Medical University · CNSun Yat-sen University · CNThe First People's Hospital of Jiangxia District · CN

Funding

Changsha Municipal Natural Science Foundation Kq2014294Fundamental Research Funds for the Central Universities 3332020062Huxiang Youth Talent support Foundation of China 2020RC3059
6 · The paper itself

Abstract

Non-melanoma skin cancer (NMSC) is the most common malignancy. Photodynamic therapy (PDT) is effective for the treatment of certain NMSCs. However, the clinical response rates of some NMSCs to single PDT are still far from ideal. The reason may be that PDT has shown limited efficacy in managing thicker NMSCs. To explore the efficacy and safety of dermabrasion combined with PDT (D-PDT) for the treatment of NMSCs. This was a retrospective, single-arm, multi-centre study. In total, 172 tumours from 40 patients were treated with D-PDT during the study period. The mean follow-up period was 40 months (range 15-110 months). D-PDT was performed with 633-nm red light at 80 m W/cm

Indexed as

Keratosis, ActinicPhotochemotherapySkin NeoplasmsAminolevulinic AcidDermabrasionHumansPhotosensitizing AgentsRetrospective StudiesTreatment OutcomeAminolevulinic AcidPhotosensitizing AgentsDermabrasionNon-melanoma skin cancerPhotodynamic therapyTreatment outcomeUltrasound

Identifiers

PMID34365550
OpenAlexW3191815308

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.