Evidence map›Paper›PMID 34365475›Full record

SynthesisJournal of perinatology : official journal of the California Perinatal Association2021

Antenatal and perinatal factors influencing neonatal blood pressure: a systematic review.

Heike Rabe, Varsha Bhatt-Mehta, Stephen A Bremner, Aisling Ahluwalia, Renske Mcfarlane, Simin Baygani, Beau Batton, Agnes Klein, Ebru Ergenekon, Luana Pesco Koplowitz and 5 more

Open access · hybridAbstract readSystematic Review
In one paragraph

Synthesis in Journal of perinatology : official journal of the California Perinatal Association, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.8field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 10 institutions in 7 countries.

Heike RabeBrighton and Sussex Medical School, University of Sussex, Brighton, UK. Heike.Rabe@nhs.net.ORCID http://orcid.org/0000-0002-2047-8875
Varsha Bhatt-MehtaFDA Center for Drug Evaluation and Research, Virginia, MD, USA.ORCID http://orcid.org/0000-0003-0085-421X
Stephen A BremnerBrighton and Sussex Medical School, University of Sussex, Brighton, UK.
Aisling AhluwaliaBrighton and Sussex Medical School, University of Sussex, Brighton, UK.ORCID http://orcid.org/0000-0003-4355-3425
Renske McfarlaneBrighton and Sussex Medical School, University of Sussex, Brighton, UK.
Simin BayganiEli Lilly and Company, Indianapolis, IN, USA.
Beau BattonSouthern Illinois University School of Medicine, Springfield, IL, USA.
Agnes KleinHealth Canada, Ottawa, ON, Canada.
Ebru ErgenekonGazi University, Ankara, Turkey.
Luana Pesco KoplowitzDUCK FLATS Pharma LLC, New York, NY, USA.
Eugene DempseyUniversity College Cork, Cork, Ireland.
Dina Apele-FreimanePauls Stradins clinical university Hospital, Marupe, Latvia.
Hiroko IwamiOsaka City General Hospital, Osaka, Japan.
Janis M DionneBritish Columbia Children´s Hospital, Vancouver, BC, Canada.ORCID http://orcid.org/0000-0003-4926-3218
International Neonatal Consortium
Brighton and Sussex Medical School · GBBC Children's Hospital · CACenter for Drug Evaluation and Research · USEli Lilly (United States) · USGazi University · TRHealth Canada · CAOsaka City General Hospital · JPPauls Stradiņš Clinical University Hospital · LVSouthern Illinois University School of Medicine · USUniversity College Cork · IE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveA comprehensive understanding of the factors contributing to perinatal blood pressure is vital to ensure optimal postnatal hemodynamic support. The objective of this study was to review existing literature on maternal and perinatal factors influencing blood pressure in neonates up to 3 months corrected age.

methodsA systematic search of published literature in OVID Medline, OVID Embase and the COCHRANE library identified publications relating to maternal factors affecting blood pressure of neonates up to corrected age of 3 months. Summary data were extracted and compared (PROSPERO CRD42018092886).

resultsOf the 3683 non-duplicate publications identified, 44 were eligible for inclusion in this review. Topics elicited were sociodemographic factors, maternal health status, medications, smoking during pregnancy, and cord management at birth. Limited data were available for each factor. Results regarding the impact of these factors on neonatal blood pressure were inconsistent across studies.

conclusionsThere is insufficient evidence to draw definitive conclusions regarding the impact of various maternal and perinatal factors on neonatal blood pressure. Future investigations of neonatal cardiovascular therapies should account for these factors in their study design. Similarly, studies on maternal diseases and perinatal interventions should include neonatal blood pressure as part of their primary or secondary analyses.

Indexed as

Blood PressureFemaleHumansInfantInfant, NewbornPregnancy

Identifiers

PMID34365475
PMCPMC8440188
OpenAlexW3183856279

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.