Evidence map›Paper›PMID 34364903›Full record

ArticleNeuropsychologia2021

Visual perception supported by verbal mediation in an individual with cerebral visual impairment (CVI).

Zahide Pamir, Corinna M Bauer, Christopher R Bennett, Barry S Kran, Lotfi B Merabet

Open access · greenAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Neuropsychologia, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Brain Connectivity During Walking and Obstacle Avoidance in Persons With Multiple Sclerosis and Healthy Controls: A Pilot EEG Study.IEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Zahide PamirThe Laboratory for Visual Neuroplasticity. Department of Ophthalmology, Massachusetts Eye and Ear, Harvard Medical School, Boston, MA, USA.
Corinna M BauerThe Laboratory for Visual Neuroplasticity. Department of Ophthalmology, Massachusetts Eye and Ear, Harvard Medical School, Boston, MA, USA.
Christopher R BennettThe Laboratory for Visual Neuroplasticity. Department of Ophthalmology, Massachusetts Eye and Ear, Harvard Medical School, Boston, MA, USA.
Barry S KranNew England College of Optometry, Boston, MA, USA; NECO Clinical Network, Perkins School for the Blind, Watertown, MA, USA.
Lotfi B MerabetThe Laboratory for Visual Neuroplasticity. Department of Ophthalmology, Massachusetts Eye and Ear, Harvard Medical School, Boston, MA, USA. Electronic address: lotfi_merabet@meei.harvard.edu.
Massachusetts Eye and Ear Infirmary · USNew England College of Optometry · US

Funding

Thalamo-cortical circuitry in PVLR01EY030877 · NEI · MASSACHUSETTS GENERAL HOSPITAL · PI BAUER, CORINNA M · 2020 to 2024
$2.1M
Neurophysiological Correlates of Visual Motion Processing in Cerebral Visual ImpairmentR01EY030973 · NEI · MASSACHUSETTS EYE AND EAR INFIRMARY · PI Lotfi Merabet · 2020 to 2026
$2.0M
Assessing Spatial Processing Deficits in Cerebral Visual Impairment (CVI) Using Virtual RealityR21EY030587 · NEI · MASSACHUSETTS EYE AND EAR INFIRMARY · PI MERABET, LOTFI · 2019 to 2020
$477k
NEI NIH HHS R01 EY030877NEI NIH HHS R01 EY030973NEI NIH HHS R21 EY030587
6 · The paper itself

Abstract

Cerebral visual impairment (CVI) often presents with deficits associated with higher order visual processing. We report a case of an individual with CVI who uses a verbal mediation strategy to perceive and interact with his visual surroundings. Visual perceptual performance was assessed using a virtual reality based visual search task combined with eye tracking. Functional magnetic resonance imaging (fMRI) was employed to identify the neural correlates associated with this strategy. We found that when using verbal mediation, the individual could readily detect and track the target within the visual scene which was associated with robust activation within a network of occipito-parieto-temporal visual cortical areas. In contrast, when not using verbal mediation, the individual was completely unable to perform the task, and this was associated with dramatically reduced visual cortical activation. This unique compensatory strategy may be related to the individual's use of verbal working memory for the purposes of understanding complex visual information.

Indexed as

Memory, Short-TermVisual PerceptionAdolescentBrain MappingCognitionHumansMagnetic Resonance ImagingMaleVision DisordersCerebral visual impairmentfMRIHigher order processingVerbal mediationVisual impairment

Identifiers

PMID34364903
PMCPMC8405572
OpenAlexW3192933289

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.