Evidence map›Paper›PMID 34364398›Full record

ArticlePorcine health management2021

Use of paracetamol in sows around farrowing: effect on health and condition of the sow, piglet mortality, piglet weight and piglet weight gain.

Wikke Kuller, Steven Sietsma, Susan Hendriksen, Daniel Sperling

Open access · goldAbstract read
In one paragraph

Article in Porcine health management, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.9field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

  1. A Review of Assessment of Sow Pain During Farrowing Using Grimace Scores.Animals : an open access journal from MDPI · 2025
    Review
  2. Article
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Wikke KullerUniversity Farm Animal Practice, Reijerscopse Overgang 1, 3481, LZ, Harmelen, The Netherlands. wkuller@ulp.nu.ORCID http://orcid.org/0000-0001-8460-786X
Steven SietsmaUniversity Farm Animal Practice, Reijerscopse Overgang 1, 3481, LZ, Harmelen, The Netherlands.
Susan HendriksenCEVA Netherlands, Ceva Santé Animale B.V, Tiendweg 8c, 2671, SB, Naaldwijk, The Netherlands.
Daniel SperlingCEVA Sante Animale, Havirna 1133, 67961, Letovice, Czech Republic.
National Farmers Union · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPain and fever in the periparturient period can lead to prolonged farrowing and can slow down the recovery of the sow, which will have an effect on the vitality and survival of the piglets. This study investigated the use of orally administered Paracetamol (Pracetam- CEVA) in sows in the periparturient period.

resultsMortality did not differ in piglets during the first week, or during total lactation (P > 0.10). No difference was found in weight or weight gain of the piglets during lactation. The coefficient of variation of piglet weight was smaller in the Paracetamol (Pm) group at day 7, day 14 and at weaning, but not at birth. So, the variation within litters was smaller in the Pm- treated sows, in comparison with the Control (C) litters. No difference in mean IgG concentration was found between treatments, but the coefficient of variation was too high (> 40) in 50% of the C litters and not in Pm litters. The Pm- treated sows lost less backfat than the C- sows. No effect was found on the body temperature of the sows, but fever was rare in both groups.

conclusionParacetamol results in less variation of body weight of piglets during lactation, seems to have a potential effect on the distribution of IgG within litters and has a positive effect on backfat loss. The effects of Paracetamol might be even more pronounced in farms with high piglet mortality (this farm only 8%) or with a high incidence of agalactia, fever after farrowing or piglet diarrhoea, which was not the case in this farm. Paracetamol is a promising product for increasing the welfare in lactating sows and optimising production in the farrowing stable.

Indexed as

FarrowingImmunocritParacetamolPigletSowWeight gainWelfare

Identifiers

PMID34364398
PMCPMC8349007
OpenAlexW3192560580

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.