Evidence map›Paper›PMID 34364260›Full record

ArticleComputers in biology and medicine2021

Effect of tube length on the buckling pressure of collapsible tubes.

M Amin F Zarandi, Kevin Garman, John S Rhee, B Tucker Woodson, Guilherme J M Garcia

Open access · greenAbstract read
In one paragraph

Article in Computers in biology and medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

M Amin F ZarandiDepartment of Biomedical Engineering, Marquette University and The Medical College of Wisconsin, 8701 Watertown Plank Road, Milwaukee, WI, 53226, United States.
Kevin GarmanDepartment of Biomedical Engineering, Marquette University and The Medical College of Wisconsin, 8701 Watertown Plank Road, Milwaukee, WI, 53226, United States.
John S RheeDepartment of Otolaryngology and Communication Sciences, Medical College of Wisconsin, 8701 Watertown Plank Road, Milwaukee, WI, 53226, United States.
B Tucker WoodsonDepartment of Otolaryngology and Communication Sciences, Medical College of Wisconsin, 8701 Watertown Plank Road, Milwaukee, WI, 53226, United States.
Guilherme J M GarciaDepartment of Biomedical Engineering, Marquette University and The Medical College of Wisconsin, 8701 Watertown Plank Road, Milwaukee, WI, 53226, United States; Department of Otolaryngology and Communication Sciences, Medical College of Wisconsin, 8701 Watertown Plank Road, Milwaukee, WI, 53226, United States. Electronic address: ggarcia@mcw.edu.
Marquette University · USMedical College of Wisconsin · US

Funding

Clinical and Translational Science AwardKL2TR000056 · NCATS · MEDICAL COLLEGE OF WISCONSIN · PI SHAKER, REZA NONE · 2012 to 2015
$609k
NCATS NIH HHS KL2 TR000056
6 · The paper itself

Abstract

backgroundThe higher incidence of obstructive sleep apnea (OSA) in men than in women has been attributed to the upper airway being longer in men. The Starling resistor is the paradigm biomechanical model of upper airway collapse in OSA where a collapsible tube (representing the pharynx) is located between two rigid tubes (representing the nasal cavity and trachea). While the Starling resistor has been extensively studied due to its relevance to many physiological phenomena, the effect of tube length on tube collapsibility has not been quantified yet.

methodsFinite element analysis of a 3-dimensional collapsible tube subjected to a transmural pressure was performed in ANSYS Workbench. The numerical methods were validated with in vitro experiments in a silicone tube whose modulus of elasticity (361 ± 28 kPa) and dimensions (length = 100 mm, diameter = 22.2 mm, and wall thickness = 1.59 mm) were selected so that tube compliance was similar to pharyngeal compliance in humans during sleep. The buckling pressure (transmural pressure at which the tube collapses) was quantified in tubes of three different diameters (10 mm, 16 mm, and 22.2 mm) and ten length-to-diameter ratios (L/D = 4 to 13), while keeping the wall-thickness-to-radius ratio constant at 0.143.

resultsThe absolute value of the buckling pressure decreased from 4.7 to 3.3 cmH

conclusionsOur finding that longer tubes are more collapsible than shorter tubes is consistent with the higher incidence of obstructive sleep apnea in males than females.

Indexed as

PharynxSleep Apnea, ObstructiveElasticityFemaleHumansMalePressureSleepAirway lengthBuckling pressureCollapsible tubesComputer simulationsFinite element analysisMechanical stabilityObstructive sleep apneaStarling resistorTube law

Identifiers

PMID34364260
PMCPMC8440427
OpenAlexW3185532998

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.