Evidence map›Paper›PMID 34364071›Full record

SynthesisClinical imaging2021

Systematic review and meta-analysis of chest radiograph (CXR) findings in COVID-19.

Zuhair Sadiq, Shehroz Rana, Ziyad Mahfoud, Ameed Raoof

Open access · hybridAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Clinical imaging, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
5.5field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 43 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Analysis of an Individualised Stepwise Approach to Non-Pharmacological Therapy in COVID-19.Respiration; international review of thoracic diseases · 2023
    Article
  12. Article
  13. Article
  14. COVID-19 pneumonia: lessons learned, challenges, and preparing for the future.Diagnostic and interventional radiology (Ankara, Turkey) · 2022
    Article
  15. Review
  16. Review
  17. Article
  18. Article
  19. Still a role for the chest radiograph - humble but helpful!African journal of thoracic and critical care medicine · 2022
    Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Zuhair SadiqWeill Cornell Medicine-Qatar, Education City, Qatar Foundation, Doha, Qatar. Electronic address: zys4001@qatar-med.cornell.edu.
Shehroz RanaWeill Cornell Medicine-Qatar, Education City, Qatar Foundation, Doha, Qatar.
Ziyad MahfoudWeill Cornell Medicine-Qatar, Education City, Qatar Foundation, Doha, Qatar.
Ameed RaoofWeill Cornell Medicine-Qatar, Education City, Qatar Foundation, Doha, Qatar.
Weill Cornell Medical College in Qatar · QA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chest radiography (CXR) is most likely to be the utilized modality for diagnosing COVID-19 and following up on any lung-associated abnormalities. This review provides a meta-analysis of the current literature on CXR imaging findings to determine the most common appearances of lung abnormalities in COVID-19 patients in order to equip medical researchers and healthcare professionals in their efforts to combat this pandemic. Twelve studies met the inclusion criteria and were analyzed. The inclusion criteria consisted of: (1) published in English literature; (2) original research study; (3) sample size of at least 5 patients; (4) reporting clinical characteristics of COVID-19 patients as well as CXR imaging features; and (5) noting the number of patients with each corresponding imaging feature. A total of 1948 patients were included in this study. To perform the meta-analysis, a random-effects model calculated the pooled prevalence and 95% confidence intervals of abnormal CXR imaging findings. Seventy-four percent (74%) (95% CI: 51-92%) of patients with COVID-19 had an abnormal CXR at the initial time of diagnosis or sometime during the disease course. While there was no single feature on CXR that was diagnostic of COVID-19 viral pneumonia, a characteristic set of findings were obvious. The most common abnormalities were consolidation (28%, 95% CI: 8-54%) and ground-glass opacities (29%, 95% CI: 10-53%). The distribution was most frequently bilateral (43%, 95% CI: 27-60%), peripheral (51%, 95% CI: 36-66%), and basal zone (56%, 95% CI: 37-74%) predominant. Contrary to parenchymal abnormalities, pneumothorax (1%, 95% CI: 0-3%) and pleural effusions (6%, 95% CI: 1-16%) were rare.

Indexed as

COVID-19HumansPandemicsRadiographyRadiography, ThoracicSARS-CoV-2Chest radiographCoronavirusCOVID-19CXRImagingMeta-analysisSARS-CoV-2

Identifiers

PMID34364071
PMCPMC8313779
OpenAlexW3184063178

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.