Evidence map›Paper›PMID 34363797›Full record

ArticleExperimental eye research2021

A spectroscopic approach to measuring meibum lipid composition and conformation in donors with Sjӧgren's syndrome.

Anthony Ewurum, Sravya R Veligandla, Jordan S Swindle, Jeremy D Clark, Douglas Borchman

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Experimental eye research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.6field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
  3. Lipid Metabolism: An Emerging Player in Sjögren's Syndrome.Clinical reviews in allergy & immunology · 2025
    Review
  4. Article
  5. Topical Application of a Novel Harderian-Derived Nonpolar Lipid Prolongs Tear Film Breakup Time in Normal Beagle Dogs.Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Anthony EwurumDepartment of Ophthalmology and Visual Sciences, University of Louisville, Louisville, KY, 40202, USA.
Sravya R VeligandlaDepartment of Ophthalmology and Visual Sciences, University of Louisville, Louisville, KY, 40202, USA.
Jordan S SwindleDepartment of Ophthalmology and Visual Sciences, University of Louisville, Louisville, KY, 40202, USA.
Jeremy D ClarkDepartment of Ophthalmology and Visual Sciences, University of Louisville, Louisville, KY, 40202, USA.
Douglas BorchmanDepartment of Ophthalmology and Visual Sciences, University of Louisville, Louisville, KY, 40202, USA. Electronic address: borchman@louisville.edu.
University of Louisville · US

Funding

Tear Film Lipid Compositional, Structural, Functional, Relationships, and Dry EyeR01EY026180 · NEI · UNIVERSITY OF LOUISVILLE · PI BORCHMAN, DOUGLAS · 2016 to 2020
$1.4M
NEI NIH HHS R01 EY026180
6 · The paper itself

Abstract

Patients with Sjӧgren's syndrome (SS) have dry eye associated with meibomian gland dysfunction (MGD). The meibum from donors with dry eye due to MGD but without SS (M

Indexed as

Lipid MetabolismAdultAgedEyelid DiseasesFemaleHumansMeibomian GlandsMiddle AgedProton Magnetic Resonance SpectroscopySjogren's SyndromeSpectroscopy, Fourier Transform InfraredTearsTissue DonorsDry eyeInfrared spectroscopyLipidsMeibumNMR spectroscopySjӧgren's syndrome

Identifiers

PMID34363797
PMCPMC8429180
OpenAlexW3182377203

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.