ArticleNeuron2021
Dynamic and reversible remapping of network representations in an unchanging environment.
Article in Neuron, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 27 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
27 citing papers in PubMed.
- Coordinated Representational Drift Across the Mouse Cortex.Research square · 2026Article
- Coordinating Cognition: The Entorhinal Cortex in Mnemonic, Temporal and Spatial Representation.Cells · 2026Review
- Coordinated Representational Drift Across the Mouse Cortex.bioRxiv : the preprint server for biology · 2026Article
- Directional dynamics in the entorhinal cortex of male mice driven by behavioral constraints.Nature communications · 2026Article
- Gaussian Process Inference Reveals Non-separability of Position and Velocity Tuning in Grid Cells.bioRxiv : the preprint server for biology · 2026Article
- SLAy-ing oversplitting errors in high-density electrophysiology spike sorting.bioRxiv : the preprint server for biology · 2025Article
- Explicit error coding can mediate gain recalibration in continuous bump attractor networks.Nature communications · 2025Article
- Spatial coding dysfunction and network instability in the aging medial entorhinal cortex.Nature communications · 2025Article
- Diverse calcium dynamics underlie place field formation in hippocampal CA1 pyramidal cells.eLife · 2025Article
- A flexible hippocampal population code for experience relative to reward.Nature neuroscience · 2025Article
- Article
- Uncovering 2-D toroidal representations in grid cell ensemble activity during 1-D behavior.Nature communications · 2024Article
- Remapping revisited: how the hippocampus represents different spaces.Nature reviews. Neuroscience · 2024Review
- Paradoxical Boosting of Weak and Strong Spatial Memories by Hippocampal Dopamine Uncaging.eNeuro · 2024Article
- Article
- Article
- A Method for Assessing Working Memory in Rats Using Controlled Virtual Environment.Sovremennye tekhnologii v meditsine · 2024Article
- Reward Expectation Reduces Representational Drift in the Hippocampus.bioRxiv : the preprint server for biology · 2023Article
- Unsupervised learning of stationary and switching dynamical system models from Poisson observations.Journal of neural engineering · 2023Article
- Ketamine evoked disruption of entorhinal and hippocampal spatial maps.Nature communications · 2023Article
Corrections and comments
- Erratum issued
Authors and funding
5 authors.
Funding
Abstract
Neurons in the medial entorhinal cortex alter their firing properties in response to environmental changes. This flexibility in neural coding is hypothesized to support navigation and memory by dividing sensory experience into unique episodes. However, it is unknown how the entorhinal circuit as a whole transitions between different representations when sensory information is not delineated into discrete contexts. Here we describe rapid and reversible transitions between multiple spatial maps of an unchanging task and environment. These remapping events were synchronized across hundreds of neurons, differentially affected navigational cell types, and correlated with changes in running speed. Despite widespread changes in spatial coding, remapping comprised a translation along a single dimension in population-level activity space, enabling simple decoding strategies. These findings provoke reconsideration of how the medial entorhinal cortex dynamically represents space and suggest a remarkable capacity of cortical circuits to rapidly and substantially reorganize their neural representations.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.