ArticleACR open rheumatology2021
High-Intensity Interval Training for Knee Osteoarthritis: A Pilot Study.
Article in ACR open rheumatology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
9 citing papers in PubMed, 1 synthesis or guideline pooled it, 14 citations in OpenAlex.
- Rates of compliance and adherence to high-intensity interval training: a systematic review and Meta-analyses.The international journal of behavioral nutrition and physical activity · 2023Pooled it
- Tolerability of high intensity interval training (HIIT) in individuals living with knee OA and at risk for cardiovascular disease: A prospective cohort study (THIPO).Osteoarthritis and cartilage open · 2026Article
- Effects of a 12-week increased hip flexion gait exercise intervention in individuals with obesity and knee osteoarthritis: a randomized crossover feasibility study.Frontiers in sports and active living · 2026Article
- Personal and General Views on Aging, Non-Communicable Diseases, and Their Interaction as Cross-Sectional Correlates of Vigorous Physical Activity in UK Individuals Aged 50.Healthcare (Basel, Switzerland) · 2025Article
- A Catalog of "Knee Friendly" Aerobic Exercises Developed for Patients With Knee Osteoarthritis: An International Patient Survey.ACR open rheumatology · 2025Article
- Non-Pharmacological Pain Management for Osteoarthritis: Review Update.Current rheumatology reports · 2025Review
- High intensity interval training attenuates osteoarthritis-associated hyperalgesia in rats.The journal of physiological sciences : JPS · 2023Article
- High-Intensity Training for Knee Osteoarthritis: A Narrative Review.Sports (Basel, Switzerland) · 2023Review
- Physical activity, physical fitness and cardiometabolic risk amongst adults with moderate and severe haemophilia.Haemophilia : the official journal of the World Federation of Hemophilia · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 3 institutions in 1 country.
Funding
Abstract
objectiveTo assess the feasibility and changes in outcomes of a 12-week high-intensity interval training (HIIT) program in individuals with symptomatic knee osteoarthritis (OA).
methodsThe single-arm trial included 29 participants (mean ± SD age 63 ± 7 years; 66% women; 66% obese). Measures of participant flow, adherence, and tolerability were collected. Pain, function, and balance were assessed at baseline, 6 weeks, and 12 weeks using the Western Ontario and McMaster Universities Osteoarthritis Index, 20-m fast-paced walk test, 30-second chair-stand test, stair-climb test, timed up and go test, and single leg stance. Cardiorespiratory fitness, strength, and body composition were evaluated using peak oxygen consumption (VO
resultsRecruitment aligned with the anticipated enrollment rate, adherence was 70%, and no adverse events were reported. At 12 weeks, improvements were observed for most outcomes, with notable mean changes for the 20-m fast-paced walk (-1.13 [95% CI -1.61 to -0.64] seconds), 30-second chair-stand (2.6 [1.8-3.4] stands), and VO
conclusionIn this 12-week pilot study, HIIT improved multiple aspects of health in individuals with knee OA; larger studies are needed.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.