Evidence map›Paper›PMID 34363590›Full record

Observational studyAging clinical and experimental research2022

Use of statins and associated factors in nonagenarians in the Community of Madrid, Spain.

Carlos Lahoz, Juan Cárdenas-Valladolid, Miguel Ángel Salinero-Fort, José María Mostaza

Open access · bronzeAbstract readObservational Study
In one paragraph

Observational study in Aging clinical and experimental research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.2field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. [Cardiovascular prevention in old age-Cardiovascular prevention of ageing?]Zeitschrift fur Gerontologie und Geriatrie · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Carlos LahozUnidad de Lípidos y Riesgo Vascular, Servicio de Medicina Interna, Hospital Universitario La Paz-Cantoblanco-Carlos III, Instituto de Investigación Sanitaria del Hospital Universitario La Paz (IdIPAZ), Madrid, Spain.
Juan Cárdenas-ValladolidFundación de Investigación e Innovación Biosanitaria de Atención Primaria, Sistemas de Información, Gerencia Asistencial de Atención Primaria, Universidad Alfonso X El Sabio, Instituto de Investigación Sanitaria del Hospital Universitario La Paz (IdiPAZ), Madrid, Spain.
Miguel Ángel Salinero-FortFundación de Investigación e Innovación Biosanitaria de Atención Primaria, Red de Investigación en Servicios de Salud en Enfermedades Crónicas (REDISSEC), Subdirección General de Investigación y Documentación, Consejería de Sanidad, Instituto de Investigación Sanitaria del Hospital Universitario La Paz (IdIPAZ), Madrid, Spain. miguel.salinero@salud.madrid.org.ORCID http://orcid.org/0000-0002-9450-4116
José María MostazaUnidad de Lípidos y Riesgo Vascular, Servicio de Medicina Interna, Hospital Universitario La Paz-Cantoblanco-Carlos III, Instituto de Investigación Sanitaria del Hospital Universitario La Paz (IdIPAZ), Madrid, Spain.
Hospital Universitario La Paz · ES

Funding

Consejería de Sanidad, Comunidad de Madrid HAC/667/2020
6 · The paper itself

Abstract

backgroundThe role of statins in the management of dyslipidemia in elderly patients with different cardiovascular risks remains unclear.

objectiveTo study use of statins and associated factors in subjects aged 90 or over in the Community of Madrid, Spain.

methodsObservational, cross-sectional study that included all people aged 90 or more residing in the Community of Madrid as of December 31, 2015. The clinical information was obtained from the database that contains the electronic medical records collected by family doctors in primary care. Comorbidity data are collected according to the International Classification of Primary Care, Second Edition (ICPC-2).

resultsThe study population comprised 59,423 subjects, with a mean age of 93.3 (2.5) years (25.8% males). Slightly more than one quarter of the population (28.2%) was in treatment with statins, 21.9% were in primary prevention, and 48.1% in secondary prevention. The multivariate analysis revealed the factors independently associated with statin treatment to be younger age, not being institutionalized, a higher Barthel score, a lower Charlson score, a higher body mass index, and a history of diabetes, dyslipidemia, chronic kidney disease, and cardiovascular disease.

conclusionsA significant percentage of nonagenarians-mainly less frail patients with more comorbidities-in the Community of Madrid receive statin treatment. No clear efficacy has been demonstrated in reducing cardiovascular events in an age group with such a short life expectancy.

Indexed as

Cardiovascular DiseasesHydroxymethylglutaryl-CoA Reductase InhibitorsAged, 80 and overCross-Sectional StudiesFemaleHumansMaleNonagenariansSpainHydroxymethylglutaryl-CoA Reductase InhibitorsAssociated factorsNonagenariansStatins

Identifiers

PMID34363590
PMCPMC8349136
OpenAlexW3187433735

What OpenQuestion holds

Texttitle and abstract
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.