Evidence map›Paper›PMID 34363588›Full record

ArticleFood and environmental virology2021

Development of a Specific Anti-capsid Antibody- and Magnetic Bead-Based Immunoassay to Detect Human Norovirus Particles in Stool Samples and Spiked Mussels via Flow Cytometry.

Ravo M Razafimahefa, Louisa F Ludwig-Begall, Mamadou Amadou Diallo, Benjamin G Dewals, Alain Vanderplasschen, Olivier Nivelles, Caroline Deketelaere, Axel Mauroy, Etienne Thiry

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In one paragraph

Article in Food and environmental virology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Ravo M RazafimahefaVeterinary Virology and Animal Viral Diseases, Department of Infectious and Parasitic Diseases, Faculty of Veterinary Medicine, FARAH Research Centre, Liège University, B43b, Quartier Vallée 2, Avenue de Cureghem, 10, B-4000, Liège, Belgium.
Louisa F Ludwig-BegallVeterinary Virology and Animal Viral Diseases, Department of Infectious and Parasitic Diseases, Faculty of Veterinary Medicine, FARAH Research Centre, Liège University, B43b, Quartier Vallée 2, Avenue de Cureghem, 10, B-4000, Liège, Belgium.
Mamadou Amadou DialloImmunology-Vaccinology, Department of Infectious and Parasitic Diseases, Faculty of Veterinary Medicine, FARAH Research Centre, Liège University, B43b, Quartier Vallée 2, Avenue de Cureghem, 10, B-4000, Liège, Belgium.
Benjamin G DewalsImmunology-Vaccinology, Department of Infectious and Parasitic Diseases, Faculty of Veterinary Medicine, FARAH Research Centre, Liège University, B43b, Quartier Vallée 2, Avenue de Cureghem, 10, B-4000, Liège, Belgium.
Alain VanderplasschenImmunology-Vaccinology, Department of Infectious and Parasitic Diseases, Faculty of Veterinary Medicine, FARAH Research Centre, Liège University, B43b, Quartier Vallée 2, Avenue de Cureghem, 10, B-4000, Liège, Belgium.
Olivier NivellesImmunology-Vaccinology, Department of Infectious and Parasitic Diseases, Faculty of Veterinary Medicine, FARAH Research Centre, Liège University, B43b, Quartier Vallée 2, Avenue de Cureghem, 10, B-4000, Liège, Belgium.
Caroline DeketelaereImmunology-Vaccinology, Department of Infectious and Parasitic Diseases, Faculty of Veterinary Medicine, FARAH Research Centre, Liège University, B43b, Quartier Vallée 2, Avenue de Cureghem, 10, B-4000, Liège, Belgium.
Axel MauroyStaff Direction for Risk Assessment, Control Policy, Federal Agency for the Safety of the Food Chain, Bld du Jardin Botanique 55, B-1000, Brussels, Belgium.
Etienne ThiryVeterinary Virology and Animal Viral Diseases, Department of Infectious and Parasitic Diseases, Faculty of Veterinary Medicine, FARAH Research Centre, Liège University, B43b, Quartier Vallée 2, Avenue de Cureghem, 10, B-4000, Liège, Belgium. etienne.thiry@uliege.be.ORCID 0000-0002-9585-7933
University of Liège · BEFederal Agency for Food Chain Safety · BE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Human noroviruses impose a considerable health burden globally. Here, a flow cytometry approach designed for their detection in biological waste and food samples was developed using antibody-coated magnetic beads. Antipeptide antibodies against murine norovirus and various human norovirus genotypes were generated for capture and coated onto magnetic beads. A flow cytometry assay was then implemented to detect bead-bound human norovirus GI.3 in patient stool samples and in norovirus-spiked mussel digestive tissues. The detection limit for stool samples was 10

Indexed as

BivalviaNorovirusAnimalsFlow CytometryHumansImmunoassayMagnetic PhenomenaMiceFlow cytometryMagnetic bead-based immunoassayMusselsNorovirusStool samples

Identifiers

PMID34363588
OpenAlexW3192499645

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.