Evidence map›Paper›PMID 34363522›Full record

ReviewSkeletal radiology2022

Imaging of treatment response and minimal residual disease in multiple myeloma: state of the art WB-MRI and PET/CT.

Frederic E Lecouvet, Marie-Christiane Vekemans, Thomas Van Den Berghe, Koenraad Verstraete, Thomas Kirchgesner, Souad Acid, Jacques Malghem, Joris Wuts, Jens Hillengass, Vincent Vandecaveye and 3 more

Open access · hybridAbstract readReview
In one paragraph

Review in Skeletal radiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 2 pooled it
4.7field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 2 syntheses or guidelines pooled it, 44 citations in OpenAlex.

  1. Guideline
  2. Pooled it
  3. Review
  4. Extramedullary Disease-Achilles Heel in Myeloma?American journal of hematology · 2026
    Review
  5. Article
  6. Article
  7. Observational
  8. Review
  9. Article
  10. Review
  11. [European journal of nuclear medicine and molecular imaging · 2024
    Article
  12. Article
  13. Imaging of Multiple Myeloma: Present and Future.Journal of clinical medicine · 2024
    Review
  14. Article
  15. Article
  16. Review
  17. First-in-Humans Evaluation of Safety and Dosimetry ofJournal of nuclear medicine : official publication, Society of Nuclear Medicine · 2023
    Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 5 institutions in 2 countries.

Frederic E LecouvetRadiology Department, Institut de Recherche Expérimentale et Clinique (IREC), Cliniques Universitaires Saint-Luc, UCLouvain, Hippocrate Avenue 10, 1200, Brussels, Belgium. frederic.lecouvet@uclouvain.be.
Marie-Christiane VekemansHaematology Unit, Cliniques Universitaires Saint-Luc, Institut de Recherche Expérimentale et Clinique (IREC), 1200, Brussels, Belgium.
Thomas Van Den BergheRadiology Department, Universiteit Ghent, Sint-Pietersnieuwstraat 33, 9000, Gent, Belgium.
Koenraad VerstraeteRadiology Department, Universiteit Ghent, Sint-Pietersnieuwstraat 33, 9000, Gent, Belgium.
Thomas KirchgesnerRadiology Department, Institut de Recherche Expérimentale et Clinique (IREC), Cliniques Universitaires Saint-Luc, UCLouvain, Hippocrate Avenue 10, 1200, Brussels, Belgium.
Souad AcidRadiology Department, Institut de Recherche Expérimentale et Clinique (IREC), Cliniques Universitaires Saint-Luc, UCLouvain, Hippocrate Avenue 10, 1200, Brussels, Belgium.
Jacques MalghemRadiology Department, Institut de Recherche Expérimentale et Clinique (IREC), Cliniques Universitaires Saint-Luc, UCLouvain, Hippocrate Avenue 10, 1200, Brussels, Belgium.
Joris WutsDepartment of Electronics and Informatics (ETRO), Vrije Universiteit Brussel, Avenue du Laerbeek 101, 1090, Jette, Belgium.
Jens HillengassDepartement of Medicine, Myeloma Unit, Park Comprehensive Cancer Center, Buffalo, NY, USA.
Vincent VandecaveyeRadiology Department, Katholieke Univesiteit Leuven, Oude Markt, 13, 3000, Leuven, Belgium.
François JamarNuclear Medicine Department, Institut de Recherche Expérimentale et Clinique (IREC), Cliniques Universitaires Saint-Luc, 1200, Brussels, Belgium.
Olivier GheysensNuclear Medicine Department, Institut de Recherche Expérimentale et Clinique (IREC), Cliniques Universitaires Saint-Luc, 1200, Brussels, Belgium.
Bruno C Vande BergRadiology Department, Institut de Recherche Expérimentale et Clinique (IREC), Cliniques Universitaires Saint-Luc, UCLouvain, Hippocrate Avenue 10, 1200, Brussels, Belgium.
Cliniques Universitaires Saint-Luc · BEGhent University · BEKU Leuven · BERoswell Park Comprehensive Cancer Center · USVrije Universiteit Brussel · BE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bone imaging has been intimately associated with the diagnosis and staging of multiple myeloma (MM) for more than 5 decades, as the presence of bone lesions indicates advanced disease and dictates treatment initiation. The methods used have been evolving, and the historical radiographic skeletal survey has been replaced by whole body CT, whole body MRI (WB-MRI) and [

Indexed as

Multiple MyelomaPositron Emission Tomography Computed TomographyFluorodeoxyglucose F18HumansMagnetic Resonance ImagingNeoplasm, ResidualPositron-Emission TomographyRadiopharmaceuticalsWhole Body ImagingFluorodeoxyglucose F18RadiopharmaceuticalsBiomarkersCancerMRIMultiple myelomaPET/CTTreatment response

Identifiers

PMID34363522
PMCPMC8626399
OpenAlexW3190662278

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.