ReviewEndocrine reviews2022
Mechanisms of Weight Loss After Obesity Surgery.
Review in Endocrine reviews, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07277465 (Role of the Microbiota in Obesity), which is not on this map. Cited by 71 papers, 6 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Role of the Microbiota in Obesity: Effect After Bariatric Surgery
Who cites it
71 citing papers in PubMed, 6 syntheses or guidelines pooled it.
- Experienced Weight Stigma Changes Following Bariatric Surgery: a Systematic Review and Meta-Analysis.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2026Pooled it
- Efficacy and safety of single-anastomosis gastric bypass variants versus sleeve gastrectomy or Roux-en-Y gastric bypass: a systematic review and meta-analysis.Updates in surgery · 2026Pooled it
- Comparative Efficacy of Metabolic/Bariatric Surgery Versus GLP-1 Receptor Agonists: A Network Meta-Analysis of Randomized Controlled Trials.Obesity (Silver Spring, Md.) · 2026Pooled it
- Pooled it
- Impact of Gastrojejunostomy Anastomosis Diameter on Weight Loss Following Laparoscopic Gastric Bypass: A Systematic Review.Obesity surgery · 2024Pooled it
- Effects of Lifestyle and Educational Bridging Programs before Bariatric Surgery on Postoperative Weight Loss: A Systematic Review and Meta-Analysis.Obesity facts · 2023Pooled it
- Distinct fasting and postprandial bile acid responses following Roux-en-Y and one-anastomosis gastric bypass.International journal of obesity (2005) · 2026Trial
- Trial
- Adaptive thermogenesis, at the level of resting energy expenditure, after diet alone or diet plus bariatric surgery.Obesity (Silver Spring, Md.) · 2024Trial
- How lipid ingestion is sensed: the mechanisms underlying intestinal hormone secretion.Clinical science (London, England : 1979) · 2026Review
- A novel approach to fat reduction: integrating traditional Chinese medicine with a dissolving MNs.Drug delivery and translational research · 2026Article
- Temporal changes in circulating metabolites after metabolic and bariatric surgery and risk of incident coronary heart disease: evidence from prospective cohort and nested case-control studies.International journal of surgery (London, England) · 2026Article
- Early Adjuvant Treatment with Semaglutide After Sleeve Gastrectomy in Patients with Class II-III Obesity: A Prospective Non-Randomized Controlled Study.Obesity surgery · 2026Article
- Synergistic Intervention for Obesity: Integrating Central Appetite Regulation and Peripheral Energy Expenditure.Current obesity reports · 2026Review
- Association between Zinc Deficiency and Medical Resource Utilization in Patients Undergoing Metabolic and Bariatric Surgery: A Retrospective Cohort Study.Obesity surgery · 2026Article
- Cardiovascular outcomes following bariatric surgery in obese patients with hypertrophic cardiomyopathy: A multicenter propensity-matched analysis.American heart journal plus : cardiology research and practice · 2026Article
- Article
- Global Trends in Bariatric Surgery for the Treatment of Metabolic Syndrome: A Bibliometric and Visualization Analysis.Obesity surgery · 2026Article
- Effect of bariatric surgery and pharmacological treatments on cardiovascular risk factors for adults with overweight and obesity: a systematic review and network meta-analysis.International journal of surgery (London, England) · 2026Article
- Bariatric and metabolic surgery improves glycolipid metabolism via bile acid regulation and intestinal barrier repair in T2DM patients.Journal of medical biochemistry · 2026Article
11 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
Obesity surgery remains the most effective treatment for obesity and its complications. Weight loss was initially attributed to decreased energy absorption from the gut but has since been linked to reduced appetitive behavior and potentially increased energy expenditure. Implicated mechanisms associating rearrangement of the gastrointestinal tract with these metabolic outcomes include central appetite control, release of gut peptides, change in microbiota, and bile acids. However, the exact combination and timing of signals remain largely unknown. In this review, we survey recent research investigating these mechanisms, and seek to provide insights on unanswered questions over how weight loss is achieved following bariatric surgery which may eventually lead to safer, nonsurgical weight-loss interventions or combinations of medications with surgery.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.