Evidence map›Paper›PMID 34363144›Full record

ArticleObesity surgery2021

Network Meta-Analysis of Metabolic Surgery Procedures for the Treatment of Obesity and Diabetes.

Andrew C Currie, Alan Askari, Ana Fangueiro, Kamal Mahawar

Registry-linked trialOpen access · bronzeAbstract readNetwork Meta-Analysis
In one paragraph

Article in Obesity surgery, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06167005 (National Introduction of One Anastomosis Gastric Bypass in the UK National Bariatric Surgery Registry), which is not on this map. Cited by 21 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 4 pooled it
6.9field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06167005 completednot on this map

National Introduction of One Anastomosis Gastric Bypass in the UK National Bariatric Surgery Registry

TypeobservationalSponsorBritish Obesity and Metabolic Surgery SocietyRan2009 to 2021Enrolled70,000ConditionsObesityArmsPrimary bariatric-metabolic surgery
3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 4 syntheses or guidelines pooled it, 40 citations in OpenAlex.

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  15. Diabetic Markers, Five Years after Bariatric Surgery.Middle East journal of digestive diseases · 2023
    Article
  16. Towards precision medicine in bariatric surgery prescription.Reviews in endocrine & metabolic disorders · 2023
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Andrew C CurrieDepartment of Bariatric Surgery, Ashford & St Peter's Hospital NHS Trust, Guildford Street, Chertsey, KT16 0PZ, UK. andrew.currie@nhs.net.
Alan AskariDepartment of Bariatric Surgery, Luton and Dunstable NHS Trust, Luton, UK.
Ana FangueiroDepartment of Bariatric Surgery, Luton and Dunstable NHS Trust, Luton, UK.
Kamal MahawarBariatric Unit, Sunderland Royal Hospital, Sunderland, UK.
Luton and Dunstable Hospital · GBAshford and St Peter's Hospitals NHS Foundation Trust · GBSunderland Royal Hospital · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMetabolic surgery is part of a well-established treatment intensification strategy for obesity and its related comorbidities including type 2 diabetes (T2DM). Roux-en-Y gastric bypass (RYGB), sleeve gastrectomy (SG) and one-anastomosis gastric bypass (OAGB) are the most commonly performed metabolic surgeries worldwide, but comparative efficacy is uncertain. This study employed network meta-analysis to compare weight loss, T2DM remission and perioperative complications in adults between RYGB, SG and OAGB.

methodsMEDLINE, EMBASE, trial registries were searched for randomised trials comparing RYGB, SG and OAGB. Study outcomes were excess weight loss (at 1, 2 and 3-5 years), trial-defined T2DM remission at any time point and perioperative complications.

resultsTwenty randomised controlled trials were included involving 1803 patients investigating the three metabolic surgical interventions. RYGB was the index for comparison. The excess weight loss (EWL) demonstrated minor differences at 1 and 2 years, but no differences between interventions at 3-5 years. T2DM remission was more likely to occur with either RYGB or OAGB when compared to SG. Perioperative complications were higher with RYGB when compared to either SG or OAGB. Two-way analysis of EWL and T2DM remission against the risk of perioperative complications demonstrated OAGB was the most positive on this assessment at all time points.

conclusionOAGB offers comparable metabolic control through weight loss and T2DM remission to RYGB and SG whilst minimising perioperative complications. Registration number: CRD42020199779 (https:// www.crd.york.ac.uk/PROSPERO ).

Indexed as

Bariatric SurgeryDiabetes Mellitus, Type 2Gastric BypassObesity, MorbidAdultGastrectomyHumansObesityRetrospective StudiesTreatment OutcomeMetabolic surgeryNetwork meta-analysisObesityType 2 diabetes

Identifiers

PMID34363144
PMCPMC8346344
OpenAlexW3187714336

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.