Evidence map›Paper›PMID 34363050›Full record

Trial reportHypertension research : official journal of the Japanese Society of Hypertension2021

Effect of intensive blood pressure lowering on left atrial remodeling in the SPRINT.

Hooman Kamel, Akm Fazlur Rahman, Wesley T O'Neal, Cora E Lewis, Elsayed Z Soliman

Abstract readRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in Hypertension research : official journal of the Japanese Society of Hypertension, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.8field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Denervation or stimulation? Role of sympatho-vagal imbalance in HFpEF with hypertension.Hypertension research : official journal of the Japanese Society of Hypertension · 2023
    Review
  3. Article
  4. Update on Hypertension Research in 2021.Hypertension research : official journal of the Japanese Society of Hypertension · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 1 country.

Hooman KamelClinical and Translational Neuroscience Unit, Feil Family Brain and Mind Research Institute, Department of Neurology, Weill Cornell Medicine, New York, NY, USA. hok9010@med.cornell.edu.
Akm Fazlur RahmanDepartments of Biostatistics, University of Alabama at Birmingham, Birmingham, AL, USA.
Wesley T O'NealDivision of Cardiology, Department of Medicine, Emory University School of Medicine, Atlanta, GA, USA.
Cora E LewisDepartment of Epidemiology, University of Alabama at Birmingham, Birmingham, AL, USA.
Elsayed Z SolimanEpidemiological Cardiology Research Center, Department of Epidemiology and Prevention, Division of Public Health Sciences and Department of Medicine, Section on Cardiology, Wake Forest School of Medicine, Winston-Salem, NC, USA.
University of Alabama at Birmingham · USEmory University · USWake Forest University · USWeill Cornell Medicine · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Upstream therapy of atrial remodeling may decrease atrial fibrillation and associated thromboembolism. We examined the impact of intensive BP lowering on ECG-defined left atrial abnormalities in the SPRINT. SPRINT was a randomized clinical trial comparing outcomes when a systolic BP of <120 mmHg (standard treatment) was the target. We included SPRINT participants without baseline atrial fibrillation who had a technically interpretable baseline ECG and at least one follow-up ECG. The primary outcome was incident left atrial abnormality, defined as P-wave terminal force in V

Indexed as

Atrial FibrillationAtrial RemodelingHypertensionAntihypertensive AgentsBlood PressureElectrocardiographyHumansRisk FactorsAntihypertensive AgentsAtrial cardiomyopathyAtrial remodelingBlood pressureHypertension

Identifiers

PMID34363050
OpenAlexW3191098509

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.