ArticleScientific reports2021
Suppression of top-down influence decreases neuronal excitability and contrast sensitivity in the V1 cortex of cat.
Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed, 10 citations in OpenAlex.
- Visual Perception and Gamma Oscillations in Cat V1 are Dynamically Correlated in Contrast Sensitivity Functions.Neuroscience bulletin · 2026Article
- Early diabetes impairs visual function in mice through altering neuronal activity in the primary visual cortex.IBRO neuroscience reports · 2026Article
- A microfluidic perspective on conventional in vitro transcranial direct current stimulation methods.Journal of neuroscience methods · 2023Review
- The effect of acupuncture at theFrontiers in integrative neuroscience · 2023Article
- Suppression of top-down influence decreases both behavioral and V1 neuronal response sensitivity to stimulus orientations in cats.Frontiers in behavioral neuroscience · 2023Article
- Effects of top-down influence suppression on behavioral and V1 neuronal contrast sensitivity functions in cats.iScience · 2022Article
- Mechanisms of Surround Suppression Effect on the Contrast Sensitivity of V1 Neurons in Cats.Neural plasticity · 2022Article
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Authors and funding
12 authors at 1 institution in 1 country.
Funding
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Abstract
How top-down influence affects neuronal activity and information encoding in the primary visual cortex (V1) remains elusive. This study examined changes of neuronal excitability and contrast sensitivity in cat V1 cortex after top-down influence of area 7 (A7) was modulated by transcranial direct current stimulation (tDCS). The neuronal excitability in V1 cortex was evaluated by visually evoked field potentials (VEPs), and contrast sensitivity (CS) was assessed by the inverse of threshold contrast of neurons in response to visual stimuli at different performance accuracy. We found that the amplitude of VEPs in V1 cortex lowered after top-down influence suppression with cathode-tDCS in A7, whereas VEPs in V1 did not change after sham-tDCS in A7 and nonvisual cortical area 5 (A5) or cathode-tDCS in A5 and lesioned A7. Moreover, the mean CS of V1 neurons decreased after cathode-tDCS but not sham-tDCS in A7, which could recover after tDCS effect vanished. Comparisons of neuronal contrast-response functions showed that cathode-tDCS increased the stimulus contrast required to generate the half-maximum response, with a weakly-correlated reduction in maximum response but not baseline response. Therefore, top-down influence of A7 enhanced neuronal excitability in V1 cortex and improved neuronal contrast sensitivity by both contrast gain and response gain.
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