Evidence map›Paper›PMID 34362953›Full record

ArticleScientific reports2021

Design and validation of fiber optic localized surface plasmon resonance sensor for thyroglobulin immunoassay with high sensitivity and rapid detection.

Hyeong-Min Kim, Dae Hong Jeong, Ho-Young Lee, Jae-Hyoung Park, Seung-Ki Lee

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.7field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 34 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Hyeong-Min KimDepartment of Electronics and Electrical Engineering, Dankook University, Yongin, 16890, South Korea.
Dae Hong JeongDepartment of Chemistry Education, Seoul National University, Seoul, 08826, South Korea.
Ho-Young LeeDepartment of Nuclear Medicine, Seoul National University Bundang Hospital, Seongnam, 13620, South Korea. debobkr@gmail.com.
Jae-Hyoung ParkDepartment of Electronics and Electrical Engineering, Dankook University, Yongin, 16890, South Korea. parkjae@dankook.ac.kr.
Seung-Ki LeeDepartment of Electronics and Electrical Engineering, Dankook University, Yongin, 16890, South Korea. skilee@dankook.ac.kr.
Dankook University · KRSeoul National University Bundang Hospital · KRSeoul National University of Education · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A simple optical fiber sensor based on localized surface plasmon resonance was constructed for direct and rapid measurement of thyroglobulin (Tg). Specific tests for Tg in patients that have undergone thyroidectomy are limited because of insufficient sensitivity, complicated procedures, and in some cases, a long time to yield a result. A sensitive, fast, and simple method is necessary to relieve the psychological and physical burden of the patient. Various concentrations of Tg were measured in a microfluidic channel using an optical fiber sensor with gold nanoparticles. The sensor chip has a detection limit of 93.11 fg/mL with no specificity for other antigens. The potential applicability of the Tg sensing system was evaluated using arbitrary samples containing specific concentrations of Tg. Finally, the sensor can be employed to detect Tg in the patient's serum, with a good correlation when compared with the commercial kit.

Identifiers

PMID34362953
PMCPMC8346482
OpenAlexW3192835091

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.