Evidence map›Paper›PMID 34362825›Full record

ArticleLife science alliance2021

Dendritic cells maintain anti-tumor immunity by positioning CD8 skin-resident memory T cells.

Jennifer L Vella, Aleksey Molodtsov, Christina V Angeles, Bruce R Branchini, Mary Jo Turk, Yina H Huang

Open access · goldAbstract read
In one paragraph

Article in Life science alliance, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 1 pooled it
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 1 synthesis or guideline pooled it, 38 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. The immunology of vitiligo.Nature reviews. Immunology · 2026
    Review
  5. Review
  6. Review
  7. Article
  8. Article
  9. Review
  10. Chemokines that govern T cell activity in tumors.Current opinion in immunology · 2025
    Review
  11. Review
  12. Article
  13. Review
  14. Article
  15. Review
  16. Review
  17. Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Jennifer L VellaDepartment of Microbiology and Immunology, Geisel School of Medicine at Dartmouth, Lebanon, NH, USA.
Aleksey MolodtsovDepartment of Microbiology and Immunology, Geisel School of Medicine at Dartmouth, Lebanon, NH, USA.
Christina V AngelesDepartment of Surgery, University of Michigan, Rogel Cancer Center, Ann Arbor, MI, USA.ORCID 0000-0002-6500-9589
Bruce R BranchiniDepartment of Chemistry, Connecticut College, New London, CT, USA.
Mary Jo TurkDepartment of Microbiology and Immunology, Geisel School of Medicine at Dartmouth, Lebanon, NH, USA.
Yina H HuangDepartment of Microbiology and Immunology, Geisel School of Medicine at Dartmouth, Lebanon, NH, USA yina.h.huang@dartmouth.edu.ORCID 0000-0002-0125-9351
Dartmouth College · USConnecticut College · USUniversity of Michigan · US

Funding

Translational Engineering in Cancer (TEC)P30CA023108 · NCI · DARTMOUTH COLLEGE · PI Fred W Kolling IV · 1985 to 2026
$91.3M
IMMUNOBIOLOGY OF MYELOID AND LYMPHOID CELLST32AI007363 · NIAID · DARTMOUTH COLLEGE · PI Claudia V Jakubzick · 1990 to 2026
$9.5M
Tissue Resident memory T cell responses to cancerR01CA225028 · NCI · DARTMOUTH COLLEGE · PI Mary Jo Turk · 2018 to 2026
$4.9M
PIP3-INDEPENDENT REGULATION OF AKT1 ACTIVITY IN T CELLSR01AI089805 · NIAID · WASHINGTON UNIVERSITY · PI HUANG, YINA HSING · 2011 to 2021
$4.2M
Olympus FV1200 Near Infrared Confocal MicroscopeS10OD021616 · OD · DARTMOUTH COLLEGE · PI STAN, RADU VIRGIL · 2016 to 2016
$321k
NCI NIH HHS P30 CA023108NCI NIH HHS R01 CA225028NIAID NIH HHS R01 AI089805NIAID NIH HHS T32 AI007363NIH HHS S10 OD021616
6 · The paper itself

Abstract

Tissue-resident memory (T

Indexed as

AnimalsBiomarkersCD8-Positive T-LymphocytesDendritic CellsDisease Models, AnimalFluorescent Antibody TechniqueHumansImmunityImmunophenotypingLymphocytes, Tumor-InfiltratingMelanomaMemory T CellsMiceBiomarkers

Identifiers

PMID34362825
PMCPMC8356251
OpenAlexW3190678177

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.