Evidence map›Paper›PMID 34362821›Full record

ArticleJournal of epidemiology and community health2021

Early adulthood socioeconomic trajectories contribute to inequalities in adult cardiovascular health, independently of childhood and adulthood socioeconomic position.

Eleanor M Winpenny, Laura D Howe, Esther M F van Sluijs, Rebecca Hardy, Kate Tilling

Abstract read
In one paragraph

Article in Journal of epidemiology and community health, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Tracking of blood pressure levels from childhood.Pediatric nephrology (Berlin, Germany) · 2025
    Review
  3. Article
  4. Article
4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

5 authors.

Eleanor M WinpennyMRC Epidemiology Unit, University of Cambridge, Cambridge, UK ew470@cam.ac.uk.ORCID 0000-0003-1933-0168
Laura D HoweMRC Integrative Epidemiology Unit, University of Bristol, Bristol, UK.
Esther M F van SluijsMRC Epidemiology Unit, University of Cambridge, Cambridge, UK.
Rebecca HardyCLOSER, Social Research Institute, UCL, London, UK.
Kate TillingMRC Integrative Epidemiology Unit, University of Bristol, Bristol, UK.

Funding

British Heart FoundationDepartment of HealthMedical Research Council MC_UU_00006/5Medical Research Council MC_UU_00011/3Medical Research Council MC_UU_12015/7Medical Research Council MR/K023187/1Medical Research Council MR/M020894/1Medical Research Council MR/T010576/1Wellcome Trust
6 · The paper itself

Abstract

backgroundCardiovascular health shows significant socioeconomic inequalities, however there is little understanding of the role of early adulthood in generation of these inequalities. We assessed the contribution of socioeconomic trajectories during early adulthood (16-24 years) to cardiovascular health in mid-adulthood (46 years).

methodsParticipants from the 1970 British Cohort Study with socioeconomic data available in early adulthood were included (n=12 423). Longitudinal latent class analysis identified socioeconomic trajectories, based on patterns of economic activity throughout early adulthood. Cardiometabolic risk factors (46 years) were regressed on socioeconomic trajectory class (16-24 years), testing mediation by adult socioeconomic position (46 years). Models were stratified by sex and adjusted for childhood socioeconomic position (SEP) and adolescent health.

resultsSix early adulthood socioeconomic trajectories were identified: (1) Continued Education (20.2%), (2) Managerial Employment (16.0%), (3) Skilled Non-manual Employment (20.9%), (4) Skilled Manual Employment (18.9%), (5) Partly Skilled Employment (15.8%) and (6) Economically Inactive (8.1%). The 'Continued Education' trajectory class showed the best cardiovascular health at age 46 years, with the lowest levels of cardiometabolic risk factors. For example, systolic blood pressure was 128.9 mm Hg (95% CI 127.8 to 130.0) among men in the 'Continued Education' class, compared with 131.3 mm Hg (95% CI 130.4 to 132.2) among men in the 'Skilled Manual' class. Patterns across classes 2-6 differed by risk factor and sex. The observed associations were largely not mediated by SEP at age 46 years.

conclusionFindings suggest an independent contribution of early adulthood socioeconomic trajectories to development of later life cardiovascular inequalities. Further work is needed to understand mediators of this relationship and potential for interventions to mitigate these pathways.

Indexed as

EmploymentSocial ClassAdolescentAdultBlood PressureCohort StudiesHumansMaleMiddle AgedRisk FactorsSocioeconomic Factorsblood pressurecardiovascular diseasesinequalitieslife course epidemiologysocial epidemiology

Identifiers

PMID34362821
PMCPMC8588297

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.