Evidence map›Paper›PMID 34362776›Full record

ReviewThe British journal of ophthalmology2023

Does real-time artificial intelligence-based visual pathology enhancement of three-dimensional optical coherence tomography scans optimise treatment decision in patients with nAMD? Rationale and design of the RAZORBILL study.

Frank G Holz, Rodrigo Abreu-Gonzalez, Francesco Bandello, Renaud Duval, Louise O'Toole, Daniel Pauleikhoff, Giovanni Staurenghi, Armin Wolf, Daniel Lorand, Andreas Clemens and 1 more

Open access · hybridAbstract readReview
In one paragraph

Review in The British journal of ophthalmology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 9 institutions in 5 countries.

Frank G HolzDepartment of Ophthalmology, University of Bonn, Bonn, Germany.
Rodrigo Abreu-GonzalezDepartment of Ophthalmology, University Hospital of La Candelaria, Santa Cruz de Tenerife, Spain.
Francesco BandelloDepartment of Ophthalmology, University Vita-Salute, Scientific Institute San Raffaele, University Vita Salute Hospital San Raffaele, Milano, Italy.ORCID 0000-0003-3238-9682
Renaud DuvalDepartment of Ophthalmology, Maisonneuve-Rosemont Hospital Research Centre, University of Montreal, Montreal, Quebec, Canada.
Louise O'TooleDepartment of Ophthalmology, Bon Secours Hospital Dublin, Dublin, Ireland.
Daniel PauleikhoffDepartment of Ophthalmology, St. Franzikus-Hospital, Münster, Germany.
Giovanni StaurenghiDipartimento di Scienze Cliniche Luigi Sacco, Eye Clinic, University of Milan, Milan, Italy.
Armin WolfDepartment of Ophthalmology, University of Ulm, Ulm, Germany.
Daniel LorandNovartis Pharma AG, Basel, Switzerland.
Andreas ClemensNovartis Pharma AG, Basel, Switzerland.ORCID 0000-0001-6192-1557
Benjamin GmeinerNovartis Pharma GmbH, Nuremberg, Germany benjamin.gmeiner@novartis.com.ORCID 0000-0002-1517-8528
Novartis (Switzerland) · CHBon Secours Hospital Dublin · IEHôpital Maisonneuve-Rosemont · CANovartis (Germany) · DESt. Franziskus Hospital · DEUniversität Ulm · DEUniversity of Bonn · DEUniversity of Milan · ITVita-Salute San Raffaele University · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background/rationaleArtificial intelligence (AI)-based clinical decision support tools, being developed across multiple fields in medicine, need to be evaluated for their impact on the treatment and outcomes of patients as well as optimisation of the clinical workflow. The

methods

conclusionsIn order to apply novel AI tools to routine clinical care, their benefit as well as operational feasibility need to be carefully investigated.

Indexed as

Refractive Surgical ProceduresTomography, Optical CoherenceAlgorithmsArtificial IntelligenceHumansObservational Studies as TopicRetinaimagingmaculaneovascularisationretinatreatment medical

Identifiers

PMID34362776
PMCPMC9763175
OpenAlexW3192659294

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.