ArticleScience advances2021
Cellular costs underpin micronutrient limitation in phytoplankton.
Article in Science advances, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 51 citations in OpenAlex.
- Effect of cellular nutrient economy on the evolution of genome size in phytoplankton.Science advances · 2026Article
- Deep Proteomic Profiles of the Antarctic Diatom Fragilariopsis Cylindrus Under Varying Iron and Manganese Conditions.Proteomics · 2026Article
- The Evolution of Southern Ocean Net Primary Production in a Changing Climate: Challenges and Opportunities.Global change biology · 2025Article
- Nitrogen status exerts dynamic control over phosphorus sensing and acquisition via PSR1 in colimited marine diatoms.Science advances · 2025Article
- Microbial reaction rate estimation using proteins and proteomes.The ISME journal · 2025Article
- Microbial reaction rate estimation using proteins and proteomes.bioRxiv : the preprint server for biology · 2024Article
- Article
- Mechanistic constraints on the trade-off between photosynthesis and respiration in response to warming.Science advances · 2023Article
- Global analysis of ocean phytoplankton nutrient limitation reveals high prevalence of co-limitation.Nature communications · 2023Article
- Process controlling iron-manganese regulation of the Southern Ocean biological carbon pump.Philosophical transactions. Series A, Mathematical, physical, and engineering sciences · 2023Article
- Manganese Limitation of Phytoplankton Physiology and Productivity in the Southern Ocean.Global biogeochemical cycles · 2022Article
- Microbial functional diversity across biogeochemical provinces in the central Pacific Ocean.Proceedings of the National Academy of Sciences of the United States of America · 2022Article
- Proteomic traits vary across taxa in a coastal Antarctic phytoplankton bloom.The ISME journal · 2022Article
- The ongoing need for rates: can physiology and omics come together to co-design the measurements needed to understand complex ocean biogeochemistry?Journal of plankton researchReview
Corrections and comments
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Authors and funding
6 authors at 4 institutions in 4 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Micronutrients control phytoplankton growth in the ocean, influencing carbon export and fisheries. It is currently unclear how micronutrient scarcity affects cellular processes and how interdependence across micronutrients arises. We show that proximate causes of micronutrient growth limitation and interdependence are governed by cumulative cellular costs of acquiring and using micronutrients. Using a mechanistic proteomic allocation model of a polar diatom focused on iron and manganese, we demonstrate how cellular processes fundamentally underpin micronutrient limitation, and how they interact and compensate for each other to shape cellular elemental stoichiometry and resource interdependence. We coupled our model with metaproteomic and environmental data, yielding an approach for estimating biogeochemical metrics, including taxon-specific growth rates. Our results show that cumulative cellular costs govern how environmental conditions modify phytoplankton growth.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.