Evidence map›Paper›PMID 34362444›Full record

ArticleEuropean journal of medical research2021

Arterial spin labeling for presurgical localization of refractory frontal lobe epilepsy in children.

Jia Zhang, Heng Zhang, Yang Li, Meng Yuan, Jinxiu Zhang, Huan Luo, Zeshan Yao, Jing Gan

Open access · goldAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in European journal of medical research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Head to head comparison between arterial spin labelling MRI and [Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2026
    Observational
  2. Review
  3. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Jia ZhangDepartment of Pediatrics, West China Second University Hospital, Sichuan University, No. 20, Section Three, South Renmin Road, Chengdu, 610041, China.
Heng ZhangDepartment of neurosurgery, West China Hospital of Sichuan University, Chengdu, 610041, China.
Yang LiDepartment of Pediatrics, West China Second University Hospital, Sichuan University, No. 20, Section Three, South Renmin Road, Chengdu, 610041, China.
Meng YuanDepartment of Pediatrics, West China Second University Hospital, Sichuan University, No. 20, Section Three, South Renmin Road, Chengdu, 610041, China.
Jinxiu ZhangDepartment of Pediatrics, West China Second University Hospital, Sichuan University, No. 20, Section Three, South Renmin Road, Chengdu, 610041, China.
Huan LuoDepartment of Pediatrics, West China Second University Hospital, Sichuan University, No. 20, Section Three, South Renmin Road, Chengdu, 610041, China.
Zeshan YaoAnlmage Technology, Beijing, China.
Jing GanDepartment of Pediatrics, West China Second University Hospital, Sichuan University, No. 20, Section Three, South Renmin Road, Chengdu, 610041, China. gordonrachel@scu.edu.cn.ORCID http://orcid.org/0000-0001-5255-6324
Sichuan University · CN

Funding

Foundation for the Development of Science and Technology Museums in China No. 2021YFS0093Foundation for the Development of Science and Technology Museums in China No. 82071686
6 · The paper itself

Abstract

backgroundEpilepsy is one of the most common chronic neurological diseases. Despite the great variety and prevalence of antiepileptic drug treatments, one-third of epilepsies remain drug resistant. The frontal lobe is extensive, and frontal lobe seizures are difficult to locate, which increases the difficulty of the preoperative localization of the epileptogenic zone. CASE PRESENTATION: Two previously healthy girls with refractory frontal lobe epilepsy showed significant perfusion abnormalities in the right frontal lobe using the cerebral blood perfusion (CBF) quantitative analysis system. They became seizure-free after lesionectomy of the frontal lobe by ASL combined with electroencephalography (EEG) rapid localization. The histopathological diagnosis was focal cortical dysplasia (FCD) type IIa and IIb.

conclusionsThe positive outcome suggests that the combined use of ASL with EEG could be a beneficial option for the presurgical evaluation of pediatric epilepsy.

Indexed as

Spin LabelsArteriesChildChild, PreschoolDrug Resistant EpilepsyElectroencephalographyEpilepsy, Frontal LobeFemaleHumansPrognosisSpin LabelsArterial spin labelingDrug-resistant epilepsyFocal cortical dysplasiaFrontal lobe epilepsyPresurgical evaluation of epilepsy

Identifiers

PMID34362444
PMCPMC8349087
OpenAlexW3192059564

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.