Evidence map›Paper›PMID 34362410›Full record

ArticleTrials2021

Impact of a medico-pharmaceutical follow-up and an optimized communication between hospital and community on the readmission to the emergency department for an adverse drug event: URGEIM, study protocol for a randomized controlled trial.

Cyril Breuker, Marie Faucanié, Marion Laureau, Damien Perier, Véronique Pinzani, Grégory Marin, Mustapha Sebbane, M Villiet

Registry-linked trialOpen access · goldAbstract readClinical Trial Protocol
In one paragraph

Article in Trials, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03725046 (Evaluation of the Impact of an Optimized Communication Between Hospital and Community on the Readmission at the Emergency Department for an Adverse Drug Event), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 54% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03725046 nacompletednot on this map

Evaluation of the Impact of an Optimized Communication Between Hospital and Community on the Readmission at the Emergency Department for an Adverse Drug Event : Randomized Controlled Trial

TypeinterventionalSponsorUniversity Hospital, MontpellierRan2018 to 2021Enrolled346ConditionsAdverse Drug EventArmsOptimized information transmission
3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Cyril Breuker *CHU Montpellier, Clinical Pharmacy Departement, Univ. Montpellier, 34 295, Montpellier Cedex 5, France. c-breuker@chu-montpellier.fr.ORCID http://orcid.org/0000-0002-9023-2686
Marie Faucanié *CHU Montpellier, Clinical Reasearch and Epidemiology Unit (Departement Information Médicale), Univ. Montpellier, 34 295, Montpellier Cedex 5, France.
Marion LaureauCHU Montpellier, Clinical Pharmacy Departement, Univ. Montpellier, 34 295, Montpellier Cedex 5, France.
Damien PerierCHU Montpellier, Emergency Medicine Department, Univ. Montpellier, 34 295, Montpellier Cedex 5, France.
Véronique PinzaniCHU Montpellier, Medical Pharmacology and Toxicology Department, Univ. Montpellier, 34 295, Montpellier Cedex 5, France.
Grégory MarinCHU Montpellier, Clinical Reasearch and Epidemiology Unit (Departement Information Médicale), Univ. Montpellier, 34 295, Montpellier Cedex 5, France.
Mustapha SebbaneCHU Montpellier, Emergency Medicine Department, Univ. Montpellier, 34 295, Montpellier Cedex 5, France.
M VillietCHU Montpellier, Clinical Pharmacy Departement, Univ. Montpellier, 34 295, Montpellier Cedex 5, France.
Université de Montpellier · FRCentre National de la Recherche Scientifique · FRInserm · FR

Funding

Direction Générale de l'offre de Soins PREPS-17-0396
6 · The paper itself

Abstract

backgroundAdverse drug events (ADE) represent one of the main causes of admission to emergency department (ED). Their detection, documentation, and reporting are essential to avoid readmission. We hypothesize that a pharmacist-initiated multidisciplinary transition of care program combining ED pharmacist contribution and medications' data transfer between inpatient and outpatient caregivers will reduce emergency visits related to ADE METHOD/

designThis is a prospective, open-label, randomized controlled trial. The primary aim of the study is 6-month ED readmission related to the same ADE. Three hundred forty-six adult patients with an ADE detected by a binomial pharmacist-physician will be recruited from the ED of an University Hospital and will be randomized in two groups: [1] experimental group (multidisciplinary transition of care program and medications' data transfer between inpatient and outpatient caregivers) and [2] control group (usual care). Patients will be followed up over a period of 6 months. Endpoints will be carried out blindly of the randomization arm. The primary endpoint is the rate of patients who had at least one readmission in the ED for the same reason at 6 months (data collected during a phone call with the patient and the general practitioner). Trials registered NCT03725046. DISCUSSION: The trial results will have implications for the role of the clinical pharmacist in an emergency department. If successful, the intervention could be considered for implementation across other hospitals.

trial registrationClinicalTrials.gov NCT03725046 . Registered on 30 October 2018.

Indexed as

Drug-Related Side Effects and Adverse ReactionsPharmaceutical PreparationsAdultCommunicationEmergency Service, HospitalFollow-Up StudiesHospitalsHumansPatient ReadmissionProspective StudiesRandomized Controlled Trials as TopicPharmaceutical PreparationsAdverse drug eventEmergency departmentPharmacist

Identifiers

PMID34362410
PMCPMC8349018
OpenAlexW3191144073

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.