Evidence map›Paper›PMID 34362399›Full record

ArticleJournal of cardiothoracic surgery2021

Localization of subcentimeter pulmonary nodules using an indocyanine green near-infrared imaging system during uniportal video-assisted thoracoscopic surgery.

Zhuo Wu, Lei Zhang, Xi-Tong Zhao, Di Zhou, Xue-Ying Yang

Abstract read
In one paragraph

Article in Journal of cardiothoracic surgery, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Indocyanine green used in association with a surgical hemostatic agent as a fiducial marker to reduce overflow during robot-assisted thoracic surgery.Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia · 2025
    Article
  5. Article
  6. Article
  7. Review
  8. Preoperative lung nodule localization: comparison of hook-wire and indocyanine green.Wideochirurgia i inne techniki maloinwazyjne = Videosurgery and other miniinvasive techniques · 2023
    Article
  9. Article
  10. Intraoperative Molecular Imaging of Lung Cancer: A Review.Surgical oncology clinics of North America · 2022
    Review
  11. Article
  12. Review
  13. Review
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Zhuo WuDepartment of Thoracic Surgery, The Fourth Affiliated Hospital of China Medical University, No.4, Chongshan East road, Shenyang, China.
Lei ZhangDepartment of Thoracic Surgery, The Fourth Affiliated Hospital of China Medical University, No.4, Chongshan East road, Shenyang, China.
Xi-Tong ZhaoDepartment of Thoracic Surgery, The Fourth Affiliated Hospital of China Medical University, No.4, Chongshan East road, Shenyang, China.
Di ZhouDepartment of Thoracic Surgery, The Fourth Affiliated Hospital of China Medical University, No.4, Chongshan East road, Shenyang, China.
Xue-Ying YangDepartment of Thoracic Surgery, The Fourth Affiliated Hospital of China Medical University, No.4, Chongshan East road, Shenyang, China. yangxy@sj-hospital.org.ORCID http://orcid.org/0000-0001-5199-9852

Funding

Scientific Research Projects of Education Department of Liaoning Province ZF2019024
6 · The paper itself

Abstract

backgroundTo investigate the feasibility of indocyanine green (ICG) use in localizing subcentimeter pulmonary nodules during uniportal video-assisted thoracoscopic surgery.

methodsThis study was a retrospective analysis of 32 patients who underwent surgery due to pulmonary nodules using ICG localization from September 2019 to March 2020 in the Department of Thoracic Surgery, The Fourth Affiliated Hospital of China Medical University. Laser positioning and large-aperture spiral CT simulation were performed preoperatively. ICG was injected into the lung (2.5 mg/ml). The clinical characteristics and postoperative indicators were recorded.

resultsA total of 33 subcentimeter pulmonary nodules were successfully localized in 32 patients. Twenty-three patients underwent lobectomy, with an average surgical time of 45.3 min and an average tube retention time of 2 days. Non-small cell lung cancer was confirmed intraoperatively in 9 patients, among whom the longest surgical time was 120 min, and the shortest hospital stay was 7 days. No patient was converted to thoracotomy or developed serious complications.

conclusionsICG imaging is a safe and effective technique for localization of pulmonary nodules. Due to the widespread application of near-infrared devices, fluorescent localization and imaging technology will be more widely used in thoracic surgery.

Indexed as

Thoracic Surgery, Video-AssistedAdultAgedCarcinoma, Non-Small-Cell LungFemaleHumansIndocyanine GreenLung NeoplasmsMaleMiddle AgedRetrospective StudiesTomography, X-Ray ComputedIndocyanine GreenIndocyanine greenPulmonary nodulesUniportal thoracoscope

Identifiers

PMID34362399
PMCPMC8348821

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.