ArticleJournal of clinical medicine2021
Can VA-ECMO Be Used as an Adequate Treatment in Massive Pulmonary Embolism?
Article in Journal of clinical medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
31 citing papers in PubMed, 1 synthesis or guideline pooled it, 41 citations in OpenAlex.
- The use of Veno-arterial Extracorporeal Membrane Oxygenation (VA-ECMO) for Acute High Risk Pulmonary Embolism: A Systematic Review.Current cardiology reviews · 2025Pooled it
- Venoarterial extracorporeal membrane oxygenation as a rescue strategy in high-risk pulmonary thromboembolism.Acute and critical care · 2026Article
- Heparin and Venoarterial Extracorporeal Membrane Oxygenation in Massive Pulmonary Embolism Management: A Case Report.The American journal of case reports · 2026Article
- ECMO-assisted catheter-directed thrombolysis for post-traumatic pulmonary embolism with bilateral atrial thrombi: a retrospective case series.Journal of cardiothoracic surgery · 2026Article
- Intraprocedural Management of Pulmonary Embolism Patients Undergoing Transcatheter Treatment, and Ventilatory and Cardiac Support.Interventional cardiology (London, England) · 2026Review
- Case Report: Pulmonary reperfusion injury with bilateral bronchial cast thrombosis after VA-ECMO-bridged catheter-based reperfusion for cardiac arrest caused by high-risk pulmonary embolism.Frontiers in cardiovascular medicine · 2026Article
- Effects of Extracorporeal Membrane Oxygenation Circuits on Drug Sequestration: A Review of Ex Vivo Experiments.Journal of clinical medicine · 2025Review
- Evolving Management of Acute Pulmonary Embolism with Extracorporeal Membrane Oxygenation-A Narrative Review.Journal of clinical medicine · 2025Review
- Advancements in Pulmonary Embolism Management: Current Approaches and Future Directions.Reviews in cardiovascular medicine · 2025Review
- Management of high-risk acute pulmonary embolism: an emulated target trial analysis.Intensive care medicine · 2025Observational
- Survival Without Neurological Sequelae Following Massive Pulmonary Embolism and Prolonged Cardiac Arrest.Cureus · 2024Article
- Thrombolysis before venoarterial ECMO for high-risk pulmonary embolism: a retrospective cohort study.Intensive care medicine · 2024Article
- Role of Extracorporeal Membrane Oxygenation in the Treatment of Massive Pulmonary Embolism.The International journal of angiology : official publication of the International College of Angiology, Inc · 2024Review
- Development and assessment of novel assist device for cardiac cannulation.International journal of computer assisted radiology and surgery · 2024Article
- Case Report: Resuscitation of patient with tumor-induced acute pulmonary embolism by venoarterial extracorporeal membrane oxygenation.Frontiers in cardiovascular medicine · 2024Article
- Veno-venous or veno-arterial extracorporeal membrane oxygenation support for massive pulmonary embolism: a case report.AME case reports · 2024Article
- Successful pharmaco-invasive approach using a lower alteplase dose and VA-ECMO support in high-risk pulmonary embolism: case report.Frontiers in cardiovascular medicine · 2024Article
- Critical Care Management of Acute Venous Thromboembolism: Integrating Pharmacotherapy, Thrombectomy, and Temporary Mechanical Support.US cardiology · 2024Review
- VA-ECOM assisted percutaneous mechanical thrombectomy treatment high-risk pulmonary embolism.Frontiers in cardiovascular medicine · 2024Article
- Extracorporeal Membrane Oxygenation for Pulmonary Embolism: A Systematic Review and Meta-Analysis.Journal of clinical medicine · 2023Review
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionMassive acute pulmonary embolism (MAPE) with obstructive cardiogenic shock is associated with a mortality rate of more than 50%. Venoarterial extracorporeal membrane oxygenation (VA-ECMO) has been increasingly used in refractory cardiogenic shock with very good results. In MAPE, although it is currently recommended as part of initial resuscitation, it is not yet considered a stand-alone therapy. MATERIAL AND
methodsAll patients with MAPE requiring the establishment of VA-ECMO and admitted to our tertiary intensive care unit were analysed over a period of 10 years. The characteristics of these patients, before, during and after ECMO were extracted and analysed.
resultsA total of 36 patients were included in the present retrospective study. Overall survival was 64%. In the majority of cases, the haemodynamic and respiratory status of the patient improved significantly within the first 24 h on ECMO. The 30-day survival significantly increased when ECMO was used as stand-alone therapy (odds ratio (OR) 15.58, 95% confidence interval (CI) 2.65-91.57,
conclusionsThe present retrospective study is certainly one of the most important in terms of the number of patients with MAPE and shock treated with VA-ECMO. This short-term mechanical circulatory support, used as a stand-alone therapy in MAPE, allows for the optimal stabilisation of patients.
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