Evidence map›Paper›PMID 34362147›Full record

ArticleJournal of clinical medicine2021

The Risk of Developing Osteoporosis in Hemolytic Anemia-What Aggravates the Bone Loss?

Leiyu Shi, Cheng-Li Lin, Ching-Huang Su, Keng-Chian Lin, Kam-Hang Leong, Yu-Ting Tina Wang, Chien-Feng Kuo, Shin-Yi Tsai

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 14 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Kruppel-like Factors in Skeletal Physiology and Pathologies.International journal of molecular sciences · 2022
    Review
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Leiyu ShiDepartment of Health Policy and Management, Johns Hopkins University Bloomberg School of Public Health, Baltimore, MD 21205, USA.
Cheng-Li LinCollege of Medicine, China Medical University, Taichung City 404, Taiwan.
Ching-Huang SuDepartment of Laboratory Medicine, Mackay Memorial Hospital, Taipei City 104, Taiwan.
Keng-Chian LinDepartment of Laboratory Medicine, Mackay Memorial Hospital, Taipei City 104, Taiwan.ORCID 0000-0002-3540-262X
Kam-Hang LeongDepartment of Laboratory Medicine, Mackay Memorial Hospital, Taipei City 104, Taiwan.
Yu-Ting Tina WangDepartment of Laboratory Medicine, Mackay Memorial Hospital, Taipei City 104, Taiwan.
Chien-Feng KuoDivision of Infectious Diseases, Department of Internal Medicine, Mackay Memorial Hospital, Taipei City 104, Taiwan.
Shin-Yi TsaiDepartment of Health Policy and Management, Johns Hopkins University Bloomberg School of Public Health, Baltimore, MD 21205, USA.ORCID 0000-0001-7978-778X
Mackay Memorial Hospital · TWJohns Hopkins University · USChina Medical University · TW

Funding

Department of Medical Research at Mackay Memorial Hospital, Taiwan MMH-106-81, MMH-107-71, MMH-107-102, MMH-107-135, MMH-109-79, MMH-109-103Mackay Medical College 1082A03Ministry of Science and Technology (MOST) Clinical Trial Consortium for Stroke MOST 108-2321-B-039-003-Taiwan Ministry of Health and Welfare Clinical Trial Center MOHW 109-TDU-B-212-114004Tseng-Lien Lin Foundation, Taichung, Taiwan
6 · The paper itself

Abstract

Hemolytic anemia (HA) renders erythropoietic stress on the bone marrow and has been linked to osteoporosis. In this nationwide retrospective cohort study, we examined this correlation by utilizing the Taiwan National Health Insurance Research Database (NHIRD). We identified two cohorts, matching population with and without HA in a 1:4 ratio. A total of 2242 HA patients and 8968 non-HA patients were enrolled. Patients with HA had a significantly higher cumulative incidence (log-rank test

Indexed as

hematopoietic stresshemolytic anemianational health insurance research databaseosteoporosis

Identifiers

PMID34362147
PMCPMC8348015
OpenAlexW3187753073

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.