ArticleJournal of clinical medicine2021
Fibromyalgia Detection Based on EEG Connectivity Patterns.
Article in Journal of clinical medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 19 citations in OpenAlex.
- Trial
- Chronic pain and oscillatory neuroplasticity: Review on impaired compensatory network responses in resting-state electroencephalography.Brain network disorders · 2026Article
- Multivariate Pattern Analysis Identifies Potential Intertrial Resting-State EEG Biomarkers in Fibromyalgia.The European journal of neuroscience · 2026Article
- Effects of Different Transcranial Direct Current Stimulation Intensities over Dorsolateral Prefrontal Cortex on Brain Electrical Activity and Heart Rate Variability in Healthy and Fibromyalgia Women: A Randomized Crossover Trial.Journal of clinical medicine · 2024Article
- Minimum and Maximum Pattern-Based Self-Organized Feature Engineering: Fibromyalgia Detection Using Electrocardiogram Signals.Diagnostics (Basel, Switzerland) · 2024Article
- Exploring Electrophysiological Responses to Hypnosis in Patients with Fibromyalgia.Brain sciences · 2024Article
- Can electroencephalography (EEG) identify the different dimensions of pain in fibromyalgia? A pilot study.BMC musculoskeletal disorders · 2024Article
- Automated characterization and detection of fibromyalgia using slow wave sleep EEG signals with glucose pattern and D'hondt pooling technique.Cognitive neurodynamics · 2024Article
- Rapid Biomarker-Based Diagnosis of Fibromyalgia Syndrome and Related Rheumatologic Disorders by Portable FT-IR Spectroscopic Techniques.Biomedicines · 2023Article
- In search of a composite biomarker for chronic pain by way of EEG and machine learning: where do we currently stand?Frontiers in neuroscience · 2023Review
- Electroencephalography functional connectivity-A biomarker for painful polyneuropathy.European journal of neurology · 2023Article
- Special Issue "Chronic Fatigue Syndrome/Myalgic Encephalomyelitis: Diagnosis and Treatment".Journal of clinical medicine · 2022Article
- Can neural markers be used for fibromyalgia clinical management?Principles and practice of clinical research (2015)Article
Corrections and comments
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Authors and funding
4 authors at 4 institutions in 1 country.
Funding
Abstract
objectiveThe identification of a complementary test to confirm the diagnosis of FM. The diagnosis of fibromyalgia (FM) is based on clinical features, but there is still no consensus, so patients and clinicians might benefit from such a test. Recent findings showed that pain lies in neuronal bases (pain matrices) and, in the long term, chronic pain modifies the activity and dynamics of brain structures. Our hypothesis is that patients with FM present lower levels of brain activity and therefore less connectivity than controls.
methodsWe registered the resting state EEG of 23 patients with FM and compared them with 23 control subjects' resting state recordings from the PhysioBank database. We measured frequency, amplitude, and functional connectivity, and conducted source localization (sLORETA). ROC analysis was performed on the resulting data.
resultsWe found significant differences in brain bioelectrical activity at rest in all analyzed bands between patients and controls, except for Delta. Subsequent source analysis provided connectivity values that depicted a distinct profile, with high discriminative capacity (between 91.3-100%) between the two groups.
conclusionsPatients with FM show a distinct neurophysiological pattern that fits with the clinical features of the disease.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.