Evidence map›Paper›PMID 34362057›Full record

ArticleJournal of clinical medicine2021

Second-Line Bismuth-Containing Quadruple Therapy for

Kiwon Shin, Min-Jae Cho, Jung-Hwan Oh, Chul-Hyun Lim

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 12 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Treatment of refractoryFrontiers in microbiology · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Kiwon ShinDepartment of Internal Medicine, College of Medicine, The Catholic University of Korea, Seoul 06591, Korea.ORCID 0000-0002-4994-223X
Min-Jae ChoDepartment of Internal Medicine, College of Medicine, The Catholic University of Korea, Seoul 06591, Korea.ORCID 0000-0002-5404-8750
Jung-Hwan OhDepartment of Internal Medicine, College of Medicine, The Catholic University of Korea, Seoul 06591, Korea.ORCID 0000-0002-9274-882X
Chul-Hyun LimDepartment of Internal Medicine, College of Medicine, The Catholic University of Korea, Seoul 06591, Korea.ORCID 0000-0002-8347-8979
Catholic University of Korea · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundBismuth-containing quadruple therapy (BQT) consisting of a proton-pump inhibitor (PPI), bismuth, metronidazole and tetracycline is recommended as a second-line treatment for

methodsThis study included 643 subjects who failed first-line STT and received 7 or 10-14 days of BQT as a second-line therapy. We retrospectively analyzed the annual

resultsThe overall eradication rates by intention-to-treat (ITT) and per-protocol (PP) analyses were 80.7% (519/643) and 93.3% (519/556), respectively. By PP analysis, the eradication rates for 2008-2011, 2012-2015, and 2016-2019 were 93.3%, 91.0%, and 96.4%, respectively (

conclusionsBQT as a second-line therapy is an effective treatment for

Indexed as

bismuthbreath testduration of therapyeradicationHelicobacter pylori

Identifiers

PMID34362057
PMCPMC8347213
OpenAlexW3185290910

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.