Evidence map›Paper›PMID 34362053›Full record

ArticleJournal of clinical medicine2021

Hospitalisation for Drug Infusion Did Not Increase Levels of Anxiety and the Risk of Disease Relapse in Patients with Inflammatory Bowel Disease during COVID-19 Outbreak.

Lorenzo Bertani, Brigida Barberio, Domenico Tricò, Federico Zanzi, Daria Maniero, Linda Ceccarelli, Ilaria Marsilio, Francesca Coppini, Greta Lorenzon, Maria Gloria Mumolo and 3 more

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 54% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 1 country.

Lorenzo BertaniDepartment of Translational Research and New Technologies in Medicine and Surgery, University of Pisa, 56100 Pisa, Italy.ORCID 0000-0001-8653-1790
Brigida BarberioDepartment of Surgery, Oncology and Gastroenterology, DISCOG, University of Padua, 35100 Padua, Italy.
Domenico TricòDepartment of Surgical, Medical and Molecular Pathology and Critical Care Medicine, University of Pisa, 56100 Pisa, Italy.ORCID 0000-0002-7633-1346
Federico ZanziDepartment of Translational Research and New Technologies in Medicine and Surgery, University of Pisa, 56100 Pisa, Italy.
Daria ManieroDepartment of Surgery, Oncology and Gastroenterology, DISCOG, University of Padua, 35100 Padua, Italy.
Linda CeccarelliDepartment of General Surgery and Gastroenterology, IBD Unit, Pisa University Hospital, 56124 Pisa, Italy.
Ilaria MarsilioDepartment of Surgery, Oncology and Gastroenterology, DISCOG, University of Padua, 35100 Padua, Italy.ORCID 0000-0003-1737-4183
Francesca CoppiniDepartment of Translational Research and New Technologies in Medicine and Surgery, University of Pisa, 56100 Pisa, Italy.
Greta LorenzonDepartment of Surgery, Oncology and Gastroenterology, DISCOG, University of Padua, 35100 Padua, Italy.ORCID 0000-0001-9378-2117
Maria Gloria MumoloDepartment of General Surgery and Gastroenterology, IBD Unit, Pisa University Hospital, 56124 Pisa, Italy.
Fabiana ZingoneDepartment of Surgery, Oncology and Gastroenterology, DISCOG, University of Padua, 35100 Padua, Italy.ORCID 0000-0003-1133-1502
Francesco CostaDepartment of General Surgery and Gastroenterology, IBD Unit, Pisa University Hospital, 56124 Pisa, Italy.
Edoardo Vincenzo SavarinoDepartment of Surgery, Oncology and Gastroenterology, DISCOG, University of Padua, 35100 Padua, Italy.ORCID 0000-0002-3187-2894
University of Padua · ITUniversity of Pisa · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

During the coronavirus disease 2019 (COVID-19) pandemic, immunomodulatory therapies and hospital admission were suspected to increase the risk of infection. Nevertheless, patients with inflammatory bowel diseases (IBD) treated with intravenous (i.v.) biologics had to move to hospitals for drug infusion. We investigated the impact of hospitalisation in patients with IBD. We conducted a survey including consecutive IBD patients initially in clinical and biochemical remission treated with biologics at the end of the first lockdown period. Patients underwent the normally scheduled clinical visits, performed at hospital for i.v.-treated patients or at home for patients treated with s.c. drugs. We administered to all patients the Hospital Anxiety and Depression Scale (HADS) questionnaire and other 12 questions, specifically related to COVID-19 and its implications. A total of 189 IBD patients were recruited, 112 (59.3%) treated with i.v. drugs and 77 (40.7%) with s.c. ones. No relapses were recorded in either group (hospitalized vs. non-hospitalized,

Indexed as

biologicsclinicalCOVID-19Crohn’s diseaseulcerative colitis

Identifiers

PMID34362053
PMCPMC8348517
OpenAlexW3187039523

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.