ReviewJournal of clinical medicine2021
Virtual Reality Interventions for Needle-Related Procedural Pain, Fear and Anxiety-A Systematic Review and Meta-Analysis.
Review in Journal of clinical medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 48 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
The Effect of Relaxation Exercise Applied With Virtual Reality Glasses on Episiotomy-induced Perineal Pain Score and Fear: A Single-Blind Randomized Controlled Study
Comparison of the Effectiveness of Two Active Distraction Methods in Reducing Pain, Fear, and Anxiety in Children Undergoing Venous Blood Sampling
Who cites it
48 citing papers in PubMed, 3 syntheses or guidelines pooled it, 139 citations in OpenAlex.
- Effectiveness of Virtual Reality in Anxiety and Pain Management in Children and Adolescents Receiving Cancer Treatment: A Systematic Review and Meta-analysis of Randomized Controlled Trials.Journal of medical systems · 2023Pooled it
- Virtual reality in chemotherapy support for the treatment of physical functions, fear, and quality of life in pediatric cancer patients: A systematic review and meta-analysis.Frontiers in public health · 2023Pooled it
- Effects of Virtual Reality-Based Distraction of Pain, Fear, and Anxiety During Needle-Related Procedures in Children and Adolescents.Frontiers in psychology · 2022Pooled it
- Comparison of the effectiveness of two active distraction methods in reducing pain, fear, and anxiety in children during venipuncture: a randomized controlled trial.BMC pediatrics · 2026Trial
- Effect of virtual reality on pain and anxiety during colonoscopy: A randomized control trial.The Journal of international medical research · 2026Trial
- Virtual Reality for the Management of Postoperative Pain and Anxiety in Children and Adolescents Undergoing Nuss Repair of Pectus Excavatum: Randomized Controlled Trial.JMIR perioperative medicine · 2026Trial
- Trial
- Distraction With Virtual Reality Goggles in Paediatric Dental Treatment: A Randomised Controlled Trial.International dental journal · 2023Trial
- A randomized controlled trial on virtual reality distraction during venous cannulation in young children.Acta anaesthesiologica Scandinavica · 2022Trial
- The Effect of Breathing Exercise Using Bubble Blower on Anxiety and Pain during Inferior Alveolar Nerve Block in Children Aged 7 to 10 Years: A Crossover Randomized Clinical Trial.Pain research & management · 2022Trial
- How can children benefit from total-body PET?The British journal of radiology · 2026Review
- Virtual reality paired with nitrous oxide for procedural pain in children: a randomized controlled trial.Pain reports · 2026Article
- Virtual reality for managing pain and fear and anxiety during pediatric needle procedures: an umbrella review.Clinical and experimental pediatrics · 2026Article
- Immediate and Short-Term Effects of Nature-Based Immersive Virtual Reality During Dry Needling: A Single-Blinded Randomized Controlled Trial.Journal of clinical medicine · 2026Article
- Dynamic assessment of pain, fear, and physiological stress during pediatric intravenous cannulation: a randomized controlled trial of virtual reality distraction.BMC nursing · 2026Article
- Virtual Reality Technology Reduces Pain and Anxiety in Hospitalized Pediatric Patients Undergoing Peripheral Venous Catheterization: A Randomized Controlled Trial.Children (Basel, Switzerland) · 2026Article
- The role of virtual reality in nasal procedures: a randomized controlled trial.Annals of medicine and surgery (2012) · 2026Article
- Effects of Cold and Vibration on Venipuncture Pain Management in Children Aged 2-7 Years Old: Randomized Controlled Trial.JMIR pediatrics and parenting · 2025Article
- Review
- Virtual Reality as an Adjuvant Treatment for Acute Pain During an Interventional Process with Capsaicin: A Feasibility Study.Journal of clinical medicine · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Needle-related procedures are often a source of pain, anxiety and fear in young patients. This systematic review aimed to investigate the effectiveness of virtual reality (VR) on reducing pain, fear and anxiety in pediatric patients undergoing needle-related procedures. Pain, anxiety, fear, changes in blood pressure and heart rate as well as satisfaction were evaluated as outcomes during needle-related procedures in VR compared with standard care conditions. A meta-analysis was performed, taking into account online databases. Two authors independently conducted literature searches in December 2020. The last search was conducted in March 2021 from a total of 106 records, 7 met our inclusion criteria. One study was excluded from the meta-analysis due to insufficient data. VR was applied as a distractor during venous access. Statistically significant benefits of using VR were shown in children's pain scores, where VR significantly decreased symptoms (
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.